Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study of Ecopipam in Children and Adolescents with Tourette Syndrome
Objective: Evaluate the efficacy and safety of ecopipam in children and adolescents with Tourette’s Syndrome (TS). Background: Ecopipam, a first-in-class selective dopamine-1 (D1) receptor antagonist…Malignant catatonia secondary to clozapine withdrawal: A case report
Objective: To report a patient with malignant catatonia from abrupt clozapine discontinuation. Background: Clozapine blocks 5HT2A/5HT2C serotonin and dopamine receptors. Cholinergic and serotoninergic rebounds have…Long-term safety and activity of ecopipam (ECO), a selective D1 antagonist during treatment of pediatric patients with Tourette Syndrome
Objective: To evaluate the long-term safety and activity of ecopipam (ECO) in the treatment of children and adolescents with Tourette syndrome (TS). Background: D2 antagonists…The association between antipsychotic-induced akathisia and suicidality: a systematic review
Objective: This systematic review aims to establish whether a causal association exists between antipsychotic-induced akathisia and suicidality, in order to guide further clinical decision making…Belly dancer’s dyskinesia due to prochlorperazine
Objective: We aim to present a case report of abdominal wall dyskinesia as a tardive syndrome of prochlorperazine. Background: The clinical presentation of involuntary choreiform…Asymmetrical resting legs tremor induced by levosulpiride
Objective: Our aim is to report unusual case of woman who presented asymmetrical resting tremor of both legs induced by levosulpiride. Background: Resting tremor of…Remote monitoring of physical activity and falls in patients with Huntington’s disease using wearable sensors
Objective: To investigate the use of a novel tele-health system to remotely monitor physical activity and falls in patients with Huntington’s disease. Background: Increased physical…Use of Inappropriate Antipsychotics Among US Long-Term Care Residents with Parkinson’s Disease Psychosis
Objective: To characterize the use of inappropriate antipsychotic therapies among residents with Parkinson’s disease psychosis (PDP) in long-term care (LTC) settings in the US. Background:…Evaluating the Inappropriate Use of Antipsychotics in Parkinson’s Disease Psychosis Patients Within Large National US Healthcare Databases
Objective: To identify Parkinson’s disease psychosis (PDP) treatment characteristics from an aggregate of US national insurer and Medicare databases. Background: Treatment of psychotic symptoms associated…Effect of dopamine D2-receptor antagonist and basal ganglia neuromodulation on neuronal activity in the cerebral motor area and cerebellar dentate nucleus
Objective: The effect of the D2-antagonist haloperidol on single unit activity (SU) and local field potentials (LFPs) of the cerebellar dentate nucleus and motor cortex…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.