Spinal cord stimulation reduces freezing of gait and improves gait in advanced Parkinson’s disease
Objective: The primary objective was to investigate the therapeutic effect of spinal cord stimulation (SCS) on gait dysfunction including freezing of gait (FOG) in advanced…Intention Awareness in Parkinson’s Disease
Objective: To investigate the role of dopamine in intention awareness of voluntary actions in patients with Parkinson’s Disease (PD). Background: Underactivation of the SMA due…Imbalance between dopaminergic and cholinergic neurotransmission following rotenone administration suggestive of Parkinson’s-like symptoms in male rats
Objective: In the present study we analyzed rotenone-induced gait abnormalities, muscular weakness and locomotor deficits in rats. The study also evaluated the effects of rotenone…Basal Ganglia Circuits for Motor and Behavioral, Emotional Performances
Objective: The present study aimed to identify which neurons in the basal ganglia (BG) target dopaminergic or GABAergic neurons in SN pars compacta (SNc) or…Rice bran extract against animal model of Huntington’s disease: Possible role of neurotransmitters
Objective: The present study has been designed to explore the effect of rice bran extract against 3-NP induced neurotoxicity in rats. Background: Huntington’s disease (HD)…MitoQ and Reduced Glutathione Protects Against Dopamine Induced Brain Mitochondrial Electron Transport Chain Inhibition During Extended In Vitro Incubation: Involvement of Free Radicals and Quinone Products
Objective: To study the impact of MitoQ and GSH against DA induced rat brain mitochondrial electron transport chain inhibition during extended in vitro incubation. Background:…Evaluation of serum sestrin protein in Parkinson’s disease: a plausible diagnostic marker
Objective: In this study, we evaluated the concentrations of sesn1 and sesn2 in the serum of 50 PD patients and 60 elderly controls. Aging is…The occurrence of dopamine-responsive and dopamine-resistant resting tremor in Parkinson’s disease
Objective: To investigate dopamine-responsiveness of resting tremor in Parkinson’s disease Background: Unlike the core Parkinson motor symptom, bradykinesia, resting tremor has a variable response to…The nature of postural tremor in Parkinson’s disease
Objective: To identify dopaminergic mechanisms underlying postural tremor in Parkinson's disease. Background: Parkinson’s tremor classically occurs at rest, but many patients also have a postural…Dopamine transporter imaging predicts motor response to dopaminergic therapy for patients with advanced Parkinson’s disease: Possible role in patient selection for subthalamic deep brain stimulation.
Objective: To investigate the possible role of dopamine transporter (DAT) imaging in patient selection for subthalamic deep brain stimulation (STN-DBS) surgery, we retrospectively investigated the…
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