Protective approach targeting NF-kB/ Nrf2 signaling and neuroinflammation using Apigenin in LPS induced Parkinsonism in experimental rats
Objective: 1. Apigenin as a protective strategy to prevent neuroinflammation in PD.2. To find behavioral, neurochemical and histopathological changes in LPS induced PD. Background: Parkinson’s…Patient-Reported Impact of Standard-of-Care: Change in Symptoms Following Dopamine Initiation and Deep Brain Stimulation
Objective: The goal of this study was to describe changes in patient-reported symptoms following initiation of standard-of-care treatment strategies in Parkinson’s disease (PD). Background: A…IMPACT OF STANDARD-OF-CARE MEDICATIONS ON TIME-OFF READOUTS IN CLINICAL TRIALS. A QUANTITATIVE SYSTEMS PHARMACOLOGY APPROACH
Objective: To mitigate clinical variability of Time-Off with various therapeutic combinations Background: There is increasing interest to use wearable-based digital health measures to continuously monitor…Comparison of Antiparkinsonian Medication Initiation and Levodopa-Equivalent Daily Dose Across PPMI, STEADY-PD III, and SURE-PD3
Objective: To compare use of antiparkinsonian medications (APM) among early Parkinson disease (PD) patients across clinical study cohorts. Background: Initiation of APM is a key…The course of tremor in de novo PD: 7 year longitudinal analysis
Objective: To longitudinally describe the course and clinical characteristics of tremor in Parkinson Disease (PD) over a seven-year follow up. Background: Tremor is a cardinal…What is holding back apomorphine therapy for Parkinson’s disease? Identifying knowledge gaps amongst Thai neurological medical professionals
Objective: To assess the level of understanding about, and identify knowledge gaps in, apomorphine therapy amongst Thai neurological medical professionals. Background: Continuous subcutaneous apomorphine infusion…Abnormal Cerebral Glucose Metabolism and Dopaminergic Dysfunction in Patients with Parkinson’s Disease with Bilateral Onset
Objective: To explore the characteristics of the abnormal cerebral glucose metabolism and dopamine distribution in patients with Parkinson's disease (PD) with bilateral onset. Background: PD is…Frequency and risk factors of dopamine agonist-induced peripheral edema in patients with Parkinson’s disease
Objective: To determine the frequency and risk factors of peripheral edema (PE) development and whether discontinuation of the drug is enough for treatment. To determine…The utility of single dose levodopa challenges in the management of Parkinson’s disease
Objective: To retrospectively review the clinical utility of single dose levodopa challenges in the management of Parkinson in a tertiary movement disorder clinic. Background: Acute…Effect of pill box organizers with alarm on improvement of adherence to pharmacotherapy in patients with Parkinson’s disease: a pilot study
Objective: To find out whether pill box organizers with alarm would improve the rate of adherence in non-adherent patients with Parkinson’s disease (PD) taking three…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.