Does the dopaminergic pathway interfere with the sustained CSF tap test effect in normal-pressure hydrocephalus?
Objective: To discuss the possible dopaminergic pathway interference as a mechanism underlying the sustained benefit of the CSF tap test in NPH. Background: The sustained…Incidence of orthostatic hypotension in Parkinson´s disease patients starting antiparkinsonian treatment
Objective: The main objetive of this study is to determine the percentage of patients diagnosed with Parkinson´s disease at Infanta Sofía University Hospital between september…Quercetin hinders Glial Activation to Alleviate the Cadmium Induced Dopaminergic Alteration via TNFα mediated CAMKIIα/ERK activation
Objective: The present study has therefore been carried out identify neuroprotective role of quercetin in alleviating the cadmium induced dopaminergic dysfunctions via glial mediated deactivation…Review of NPO status on admitted PD patient outcomes
Objective: To characterize the incidence and severity of outcomes for PD patients admitted to the hospital who miss doses of their medication. Background: PD is…Protective approach targeting NF-kB/ Nrf2 signaling and neuroinflammation using Apigenin in LPS induced Parkinsonism in experimental rats
Objective: 1. Apigenin as a protective strategy to prevent neuroinflammation in PD.2. To find behavioral, neurochemical and histopathological changes in LPS induced PD. Background: Parkinson’s…Gold and silver nanoparticle-based Localized Surface Plasmon Resonance Sensor (LSPR) for the detection of histidine as a potential biomarker in Parkinson’s Disease.
Objective: Previous literature has proven that histamine has a crucial role in the process of neuroinflammation in Parkinson's Disease (PD) . We can indirectly detect…Patient-Reported Impact of Standard-of-Care: Change in Symptoms Following Dopamine Initiation and Deep Brain Stimulation
Objective: The goal of this study was to describe changes in patient-reported symptoms following initiation of standard-of-care treatment strategies in Parkinson’s disease (PD). Background: A…IMPACT OF STANDARD-OF-CARE MEDICATIONS ON TIME-OFF READOUTS IN CLINICAL TRIALS. A QUANTITATIVE SYSTEMS PHARMACOLOGY APPROACH
Objective: To mitigate clinical variability of Time-Off with various therapeutic combinations Background: There is increasing interest to use wearable-based digital health measures to continuously monitor…Comparison of Antiparkinsonian Medication Initiation and Levodopa-Equivalent Daily Dose Across PPMI, STEADY-PD III, and SURE-PD3
Objective: To compare use of antiparkinsonian medications (APM) among early Parkinson disease (PD) patients across clinical study cohorts. Background: Initiation of APM is a key…The course of tremor in de novo PD: 7 year longitudinal analysis
Objective: To longitudinally describe the course and clinical characteristics of tremor in Parkinson Disease (PD) over a seven-year follow up. Background: Tremor is a cardinal…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.