Ibudilast, a Phosphodiesterase Inhibitor, Alleviates Huntington’s Disease Pathology through Neuroinflammation Modulation and Signaling Pathway Regulation in a Rat Model
Objective: This research aims to assess whether Ibudilast (IBD), a phosphodiesterase IV (PDE IV) inhibitor, can mitigate the damage induced by 3-nitropropionic acid (3-NP) in…Neuroprotective Efficacy of Ethanolic Extract from Amorphophallus Paeoniifolius Tuber Against Haloperidol-Induced Parkinson’s Disease Model
Objective: This study aimed to evaluate the neuroprotective and antiparkinsonian effects of the ethanolic extract of Amorphophallus paeoniifolius tuber (APT) against haloperidol-induced Parkinson’s Disease (PD)…Can optical coherence tomography differentiate Parkinson’s disease from drug-induced parkinsonism?
Objective: We aimed to determine whether optical coherence tomography (OCT) findings could differentiate DIP from Parkinson’s disease (PD). Background: Drug-induced parkinsonism (DIP) is common, but…Tramadol Induces Neuroinflammation, Mitochondrial Oxidative Stress, Neurotransmitters Dysbalanced and Produced Parkinson’s Disease Like Symptoms in Experimental Wistar Rats
Objective: The current study is designed to evaluate the possible neurotoxic effects of tramadol in Wistar rats. Background: Parkinson’s disease (PD) is a chronic neurodegenerative…Severe tacrolimus-induced parkinsonism after kidney transplantation
Objective: To describe a kidney transplant recipient with severe tacrolimus-induced parkinsonism. Background: Kidney transplant recipients have to adhere to strict immunosuppressive regimens, which generally include…Pharmacological Invivo and invitro potential of resveratrol in experimental rat models of Parkinson’s disease
Objective: Aim of study was to elucidate the pharmacological Invivo and invitro effects and mechanisms of action ofRT in experimental models of PD. Background: The…Role of nanoparticles of berberine on oxidative stress in nigrostriatal tissue and neurobehavioral characteristics in rotenone induced animal model of Parkinson’s disease
Objective: The current study exemplified the therapeutic potential of solid lipid nanoparticles (SLN) of berberine (BE-SLN) against oxidative stress in nigrostriatal tissue and neurobehavioral characteristics…Clinical Profile Of Drug-Induced Movement Disorders In Cipto Mangunkusumo Hospital, Indonesia
Objective: We aimed to portray the clinical spectrum of Drug-induced movement disorders (DIMDs) in Cipto Mangunkusumo Hospital, Jakarta, Indonesia Background: DIMDs remain a significant burden…Drug-induced Parkinsonism and nonmotor symptoms: a case of gustatory rhinorrhea
Objective: We aim to emphasize the relevance of contemplating nonmotor symptoms as possible features of drug-induced parkinsonism, and the utmost importance of further investigation in…Olfactory discrimination differentiate drug-induced parkinsonism and Parkinson’s disease
Objective: In this study, we evaluated detailed differential features of olfactory function in PD and DIP. Background: DIP is common but it is challenging to…
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