Levodopa-induced dyskinesias and substantia nigra dopamine D3 receptor availability in Parkinson’s disease
Objective: To investigate with PET and the radioligand [11C]PHNO whether levodopa-induced dyskinesias in Parkinson disease (PD) are associated with dopamine-D3 receptor (D3R) overexpression in substantia nigra…Efficacy and tolerability of opicapone in Parkinson´s disease in usual clinical practice
Objective: To evaluate the efficacy and tolerability of opicapone in usual clinical practice in patients with Parkinson's disease (PD). Background: Opicapone is a recently approved…Smartphone-based context awareness to improve ambulatory Parkinson’s monitoring
Objective: To determine the utility of context-awareness algorithms based on sensors in smartphones to improve ambulatory Parkinson’s disease (PD) monitoring. Background: Previous research shows that optimal motion sensor-based ambulatory PD monitoring requires multiple sensors to…Abnormal network interconnections dynamics correlate with levodopa-induced dyskinesia in Parkinson’s disease
Objective: To explore the pathogenesis of dyskinesia, the present study was conducted to investigate that how large-scale functional network interactions change dynamically in the temporal…Impact of dopamine 2/3 receptor agonists on the phenomenology of L-DOPA-induced dyskinesia in patients with Parkinson’s disease
Objective: To investigate possible differences in phenomenology and temporal profile of dyskinesias in patients with Parkinson’s disease (PD) after challenge doses with levodopa alone or…Use in Clinical Practice of a Personalised and Long-term Monitoring Device for Parkinson´s Disease: STAT-ON
Objective: To analyze the opinion of different neurologists from Spain about the STAT-ON tool after using the device in a real clinical practice setting (RCPS).…Dysfunction in superior frontal gyrus associated with diphasic dyskinesia in Parkinson’s disease
Objective: We aimed to explore alterations in regional brain function associated with diphasic dyskinesia in Parkinson’s disease (PD). Background: Levodopa-induced dyskinesia (LID), which is a common…Pharmacokinetics of Levodopa in patients with Parkinson’s disease: Efforts toward a predictive model
Objective: Our aim was to explore correlations between the pharmacokinetics of levodopa (LD) and clinical manifestation in patients with Parkinson’s disease (PD). Our goal was…Towards a method for accurate detection of diphasic dyskinesia
Objective: The present study aims to evaluate the efficacy of a body-worn sensor device to detect leg repetitive abnormal movements in patients with Parkinson's disease…Lack of depotentiation may not be a hallmark of Levodopa-induced dyskinesias
Objective: Paired associative stimumlation (PAS)-induced plasticity, a form of spike-time dependent plasticity (STDP), is deficient in PD. We tested whether (1) PAS-induced plasticity could be…
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