Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism
Objective: We set out to compare patterns of dyskinetic behaviours induced by the systemic administration of L-DOPA and D1 or D2 receptor (D1R, D2R) agonists…Wearable sensor motor outcomes across patients with Parkinson’s disease from Asian, Black, and Caucasian ethnicity in the United Kingdom
Objective: To determine the effect of ethnic background on motor scores in people with Parkinson’s disease (PwP) using objective measurement. Background: Limited evidence has suggested…The influence of culture on the relationship between subjective and objective assessments of dyskinesia severity.
Objective: To explore the relationship and rate of agreement between patient and clinician evaluation of dyskinesia severity and impact on function across multiple cultures. Background:…A Case of Autoimmune Orofacial Dyskinesia associated with Striational Antibody
Objective: This is a case of steroid-responsive, autoimmune orofacial dyskinesia associated with extremely elevated striational [striated muscle] antibody. We present this instructive case to add…Local Field Potentials (LFP) used to guide treatment of biphasic dyskinesias in a patient with Parkinson’s Disease (PD)
Objective: To identify, characterize and treat dyskinesias and off time in a patient with PD via the use of gamma and beta peak LFP using…Deep brain stimulation of the pallidofugal pathways to rescue severe brittle dyskinesias after STN-DBS lead implantation
Objective: To present a case with a severe life-threatening microlesion effect related with STN DBS rescued with a tractography-guided neuromodulation approach Background: Microlesion effect have…Hyperkinetic Movement Disorders after Thalamic Lesions
Objective: To describe delayed hyperkinetic movement disorder after a thalamic lesion. Background: Lesions in the basal ganglia circuit can cause abnormal movement disorders. After thalamic…Hemiparkinsonism Due to Diencephalic Lesion with 24 Years of Levodopa Response and Only Mild Dyskinesia
Objective: To present a case of a long-standing hemiparkinsonism due to cerebral lesion with a continuous response to a stable dose of levodopa with only…Ziconotide-Induced Orolingual Dyskinesia: A Case Series
Objective: Our aim is to report three cases of orolingual dyskinesia in adults receiving intrathecal ziconotide for chronic pain management. Background: Ziconotide (ZCN), a nonopioid…Effect of Levodopa-Carbidopa Intestinal Gel Versus Optimized Medical Treatment on Dyskinesia in Advanced Parkinson’s Disease Patients: Final Results of the Randomized 12-Week DYSCOVER Study
Objective: This study evaluated the effectiveness of LCIG versus optimized medical treatment (OMT) on the duration and severity of dyskinesia in aPD patients. Background: Approximately…
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