High levodopa plasma concentration in the acute levodopa challenge test predicts levodopa-induced dyskinesia in Parkinson’s disease
Objective: We aimed to investigate the correlation between levodopa pharmacokinetics and levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD). Background: In patients with PD, pulsatile dopaminergic…Advanced autonomous motor state detection from wrist-worn sensor in persons with PD
Objective: To explore the advancement of precision and granularity of motor state detection in persons with PD (PwP) from wrist-worn sensor data. Background: The motor…OPICAPONE: REAL WORLD EVIDENCE IN TOLEDO´S MOVEMENT DISORDERS UNIT
Objective: We present a prospective observational-real life study about the use in Movement Disorders Unit´s patients, since its commercialization in Spain (June 2017). Background: The…Motor and non-motor symptoms burden, autonomy, quality of life and principal caregiver status is worse in patients with 5-2-1 positive criteria: a simple screening tool for identifying PD patients who need an optimization of Parkinson´s treatment.
Objective: To compare quality of life (QoL), non-motor symptoms (NMS) burden, autonomy for activities of daily living (ADL) and patient´s principal caregiver status in PD…Predicting the impact of Parkinson’s disease on a patient’s gait: the potential of innovative approaches based on instrumented clinical tests
Objective: To investigate the potential to predict the impact of the patient’s symptomatology on his ability to walk. Specifically, we (1) formed clusters of performance…Interleaved deep brain stimulation for dyskinesia management in Parkinson’s disease
Objective: To evaluate the clinical effects of using interleaving stimulation to simultaneously treat Parkinson’s disease (PD) symptoms and dyskinesia by the generation of two symptom-specific…Impulse control and repetitive behavior disorders are more common in PD patients with levodopa-induced dyskinesias
Objective: Our aim was to evaluate the prevalence of impulse control and repetitive behavior disorders (ICRB) in patients affected by Parkinson's disease (PD) with and without levodopa-induced…Biphasic Dyskinesias in Parkinson’s disease Patients treated with Levodopa/Carbidopa Intestinal Gel: Insights from a Multicenter Retrospective Analysis
Objective: We aimed to characterize Parkinson's disease (PD) patients who developed the onset of new troublesome dyskinesias after Levodopa-Carbidopa Intestinal Gel (LCIG) initiation. We were…The effect of levodopa on speech in advanced Parkinson’s Disease: acoustic analysis and correlation with motor features and dyskinesia
Objective: Analyse the effects of levodopa on speech and its possible relationship with motor features and dyskinesias in a group of advanced Parkinson’s disease (PD)…Objective assessment of motor states in Parkinson’s disease using partial least squares and smartphone data
Objective: In this study, we will investigate the behaviour of Partial Least Squares (PLS) regression for dimension reduction and prediction of motor states of Parkinson’s…
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