STN-DBS programing for dyskinesia: a case report
Objective: To investigate the effect of STN stimulation on different types of dyskinesia and programming strategy. Background: Long-term use of levodopa or dopamine agonists often…Memantine induced dyskinesia in Alzheimer’s disease
Objective: There is only little evidence for memantine induced dyskinesia in Alzheimer’s disease. We present a patient with Alzheimer’s disease who developed choreatic dyskinesia as a result…LY-341,495, an mGlu2/3 antagonist, abolishes the anti-dyskinetic and anti-psychotic effects of the mGlu2/3 orthosteric agonist LY-354,740 in the MPTP-lesioned marmoset
Objective: We aim to determine the effect of orthosteric blockade of metabotropic glutamate 2 and 3 (mGlu2/3) receptors with LY-341,495 on the anti-dyskinetic and anti-psychotic…Inhibitory Repetitive Transcranial Magnetic Stimulation of Pre-Supplementary Motor Area Improves Levodopa-Induced Dyskinesia in Parkinson’s Disease
Objective: To prove the causal role of pre-supplementary motor area (preSMA) in levodopa-induced dyskinesia using an interventional brain stimulation approach that targets abnormal preSMA activity. Background:…Moving ear syndrome secondary to bromopride and response to botulinum toxin
Objective: Report a case of a rare drug-induced movement disorder, the moving ear syndrome, describe its phenomenology and its treatment with botulinum toxin Background: Since…The effect of levodopa-carbidopa intestinal gel relative to optimized medical treatment on dyskinesia: Design and baseline characteristics for an open-label, randomized multicenter 12-week study in advanced Parkinson’s disease patients (DYSCOVER Study)
Objective: The DYSCOVER study will be the first interventional, randomized study to evaluate the comparative effectiveness of levodopa-carbidopa intestinal gel (LCIG) versus optimized medical treatment…Safinamide ameliorates motor deficits and plastic alterations before the onset of L-DOPA-induced dyskinesia in a rat model of Parkinson’s disease
Objective: To investigate the effects of safinamide (saf) on synaptic plasticity of spiny projection neurons (SPNs) and the antiparkinsonian effect in dopamine (DA) denervated rats…Liquid Levodopa/Carbidopa – An underutilized, cost effective treatment of advanced Parkinson’s disease in the developing world
Objective: Advanced Parkinson’s disease manifests with “on-off” phenomenon, dyskinesias and increasing symptom severity . Managing it in developing countries is difficult given the low per…An unusual cause of rhabdomyolysis in the patients with Parkinson’s disease: A report of two cases
Objective: To describe unusual cause of rhabdomyolysis in the two patients with Parkinson’s disease (PD). Background: Levodopa-induced dyskinesia (LID) is usually seen in advanced stage…Randomized, placebo-controlled, double-blind, two-period cross-over study to evaluate the safety, tolerability, and efficacy of a novel treatment combination for levodopa induced dyskinesia in Parkinson’s Disease (BUS-PD)
Objective: To evaluate the efficacy of buspirone in combination with amantadine in reducing levodopa-induced dyskinesia (LID) in patients with Parkinson’s disease (PD). Background: LID is…
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