Predicting the impact of Parkinson’s disease on a patient’s gait: the potential of innovative approaches based on instrumented clinical tests
Objective: To investigate the potential to predict the impact of the patient’s symptomatology on his ability to walk. Specifically, we (1) formed clusters of performance…Interleaved deep brain stimulation for dyskinesia management in Parkinson’s disease
Objective: To evaluate the clinical effects of using interleaving stimulation to simultaneously treat Parkinson’s disease (PD) symptoms and dyskinesia by the generation of two symptom-specific…Advanced autonomous motor state detection from wrist-worn sensor in persons with PD
Objective: To explore the advancement of precision and granularity of motor state detection in persons with PD (PwP) from wrist-worn sensor data. Background: The motor…Biphasic Dyskinesias in Parkinson’s disease Patients treated with Levodopa/Carbidopa Intestinal Gel: Insights from a Multicenter Retrospective Analysis
Objective: We aimed to characterize Parkinson's disease (PD) patients who developed the onset of new troublesome dyskinesias after Levodopa-Carbidopa Intestinal Gel (LCIG) initiation. We were…The effect of levodopa on speech in advanced Parkinson’s Disease: acoustic analysis and correlation with motor features and dyskinesia
Objective: Analyse the effects of levodopa on speech and its possible relationship with motor features and dyskinesias in a group of advanced Parkinson’s disease (PD)…Objective assessment of motor states in Parkinson’s disease using partial least squares and smartphone data
Objective: In this study, we will investigate the behaviour of Partial Least Squares (PLS) regression for dimension reduction and prediction of motor states of Parkinson’s…Dopamine dysregulation syndrome and levodopa-induced dyskinesias in patients with Parkinson’s disease on the background of deep stimulation of the subthalamic nucleus
Objective: Assessment of the dynamics of the clinical manifestations of dofamine dysregulation syndrome (DDS) and the severity of dyskinesias in patients with Parkinson`s Disease (PD)…Impulse control and repetitive behavior disorders are more common in PD patients with levodopa-induced dyskinesias
Objective: Our aim was to evaluate the prevalence of impulse control and repetitive behavior disorders (ICRB) in patients affected by Parkinson's disease (PD) with and without levodopa-induced…Efficacy and safety of the 5-Hydroxytryptophan on Levodopa-Induced Motor Complications in Parkinson’s disease.
Objective: To evaluate the efficacy of the 5-Hydroxytryptophan (5-HTP) on levodopa-induced motor complications in patients with Parkinson's disease (PD). Background: Several studies have indicated that…Wearable sensor use and monitoring effect of dopamine replacement therapy on motor parameters in a real life clinical setting
Objective: To explore the usefulness of wearable sensor data to inform treatment decisions in PD. Background: Wearable sensors are becoming increasingly incorporated into clinical care…
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