Interaction between mGluR5 and NR2B is increased in 6-OHDA parkinsonian rats with L-dopa-induced dyskinesiaInteraction between mGluR5 and NR2B is increased in 6-OHDA parkinsonian rats with L-dopa-induced dyskinesia
Objective: In this study, we verified whether the interaction of mGluR5 and NR2B exerts an important effect on the development of LID. Background: L-dopa is…Ondansetron, a highly-selective 5-HT3 receptor antagonist, alleviates L-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson’s disease
Objective: To determine the effectiveness of selective serotonin 3 (5-HT3) receptor blockade at reducing the severity of established, and preventing the development of, dyskinesia. Background:…Assessing the potential cost-effectiveness of ads-5102 (Amantadine HCl) for the treatment of dyskinesia in Parkinson’s disease patients
Objective: This economic evaluation projects the likely cost-effectiveness of ADS-5102 in comparison to the current standard of best supportive care. Background: In August, 2017, the…Neutrophil to lymphocyte ratio, lymphocyte to monocyte ratio and Parkinson’s Disease: Preliminary report
Objective: We conducted a pilot study to determine the association between the neutrophil to lymphocyte ratio (NLR), he lymphocyte to monocyte ratio (LMR), the levels…Mild to moderate dyskinesia is not significantly related to the level of activity engagement or quality of life of patients with Parkinson’s disease
Objective: This cross-sectional study aimed at determining the relation between levels of drug-induced dyskinesia (DID), tremor, rigidity, bradykinesia, postural instability, as well as cognition and…Does motor laterality affect the development of dyskinesia in patients with Parkinson’s disease?
Objective: To investigate the effects of motor laterality on the development of levodopa-induced dyskinesia (LID) in patients with de novo Parkinson’s disease (PD). Background: LID…The scaling properties of chorea and levodopa-induced dyskinesia are similar to voluntary movements
Objective: Explore whether levodopa-induced dyskinesia (LID) and chorea share voluntary movement characteristics to better understand the mechanisms underlying these involuntary movements. Background: We have recently…Prevalence and risk factor of peak-dose dyskinesia in Thai patients with Parkinson’s disease
Objective: To determine the prevalence and risk factors associated with peak-dose dyskinesia in Thai patients with Parkinson’s disease. Background: Dyskinesias are involuntary movement that interfere…Impact of levodopa-induced dyskinesias on Health-related Quality of Life. Results from the French COPARK study.
Objective: To assess the impact of LIDs on HRQoL in this large sample of unselected Parkinson’s Disease (PD) patients and to assess the factors related…Protocol for upper-limb kinematic analysis in paediatric movement disorders and relative normality data
Objective: The study proposes a specialised protocol to collect and analyse kinematic data from paediatric patients affected by Movement Disorders (MD). The aim is to…
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