MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dystonia: Pathophysiology"

  • 2025 International Congress

    White matter alterations in Yeo’s motor network correlate with kinematic writing behavior in writer’s cramp dystonia

    A. Murlikrishnan, B. Dahlben, M. Lutz, S. Davis, C. Mcintyre, N. Bukhari-Parlakturk (Durham, USA)

    Objective: To investigate the relationship between white matter changes in the motor network and kinematic writing measures in WC and healthy volunteers (HV). Background: Writer’s…
  • 2025 International Congress

    Central Neuromodulatory Effects of Sodium Oxybate in Laryngeal Dystonia: A Pharmacological fMRI Study

    L. O'Flynn, A. Hamzehei Sichani, A. Worthley, N. Sharma, P. Song, K. Simonyan (Boston, USA)

    Objective: To examine the central effects of sodium oxybate in patients with alcohol-responsive (EtOH+) laryngeal dystonia (LD). Background: LD is a task-specific form of isolated…
  • 2025 International Congress

    Multimodal Neurophysiological Evaluation in Patients with Different Dystonia Subtypes

    T. Grippe, N. Sheth, A. Bhattacharya, JC. Chen, N. Raies, H. Taskin, N. Naeini, R. Annirood, JF. Nankoo, J. Baarbe, R. Chen (Toronto, Canada)

    Objective: Evaluate dystonia patients with different subtypes using a standardized neurophysiological test battery. Background: Dystonia pathophysiology is characterized by circuit dysfunction involving the thalamus, basal…
  • 2025 International Congress

    Clinical Improvement after Deep Brain Stimulation is associated with the Suppression of Pallidal low-frequency Oscillations in Patients with Dystonia

    C. Palmisano, J. Del Vecchio, I. Hanafi, A. Al Habbal, C. Matthies, G. Pezzoli, J. Volkmann, P. Capetian, N. Pozzi, S. Haufe, I. Isaias (Wuerzburg, Germany)

    Objective: to investigate the relationship between pallidal activity and clinical response to deep brain stimulation (DBS) of the globus pallidus internus (GPi) Background: GPi-DBS is…
  • 2025 International Congress

    Focal Lower Limb Myoclonus Heralding Adult Onset Fulminant SSPE

    S. Jha, S. Pendyala (Kolkata, India)

    Objective: We report a case adult onset fulminant SSPE with focal lower limb myoclonus as the predominant presenting movement disorder. Background: Myoclonus remains a defining…
  • 2025 International Congress

    Status Dystonicus is a Distinct State Characterized by Pallidal Beta-band Activity

    A. Balachandar, L. Vogt, K. Mithani, S. Coleman, M. Ebden, A. Leblanc-Miller, S. Breitbart, A. Fasano, C. Gorodetsky, G. Ibrahim (Toronto, Canada)

    Objective: To identify distinct pallidal local field potential (LFP) signatures characterizing status dystonicus (SD) from non-SD dystonia. Background: SD is a poorly understood neurological emergency…
  • 2025 International Congress

    GPi Stimulation shows Immediate Effects in Motor Improvement within Pediatric Patients with Movement Disorders

    A. Brucker, A. Zakharova, S. Seyyed Mousavi, A. Salisbury, J. Olaya, M. Liker, T. Sanger (Orange, USA)

    Objective: This study was conducted in order to determine whether GPi stimulation has immediate clinical effect in patients with dystonia who underwent Deep Brain Stimulation…
  • 2025 International Congress

    Cerebellar connectivity predicts early response to GPi-DBS in dystonia.

    A. Martinez Nunez, V. Chandra, C. Fleeting, A. Patel, A. Fusco, J. Wong (Gainesville, USA)

    Objective: To investigate the structural and functional connectivity of patients who respond early after deep brain stimulation (DBS) for dystonia. Background: DBS is an effective…
  • 2024 International Congress

    Structural and Functional Brain Alterations in Laryngeal Dystonia: A Coordinate-Based Activation Likelihood Estimation Meta-Analysis

    N. Kshatriya, G. Battistella, K. Simonyan (Boston, USA)

    Objective: Efforts to understand laryngeal dystonia (LD) pathophysiology using neuroimaging techniques have demonstrated altered brain structure and function in patients compared to healthy controls1-5. However,…
  • 2024 International Congress

    Task-Based Functional Imaging in Task-Specific Focal Dystonia during Dystonia-Related and -Unrelated Tasks

    B. Huynh, Y. Wang, M. Chen, E. Narinsky, YL. Kuo, T. Kimberley (Boston, USA)

    Objective: To use task-based functional magnetic resonance imaging [fMRI] to examine body region-specific sensorimotor changes with the long-term goal of identifying potential unifying pathophysiological fMRI features…
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