MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dystonia: Pathophysiology"

  • MDS Virtual Congress 2021

    Multifractal spectrum width of pallidal activity correlates with dystonic severity

    U. Semenova, V. Popov, R. Medvednik, A. Tomskiy, A. Sedov (Moscow, Russian Federation)

    Objective: To examined whether multifractal properties of pallidal activity correlate with dystonic symptom severity across patients. Background: The internal segment of globus pallidus (GPi) is…
  • MDS Virtual Congress 2021

    Neural Signals in the Cerebellar Nuclei Gate the Manifestation of Dystonia-Associated Symptoms in Mice

    M. Vander Heijden, T. Lin, D. Kizek, A. Brown, R. Sillitoe (Houston, USA)

    Objective: Define the differences in electrophysiological signatures of cerebellar output between mouse models of dystonia with diverse severity and manifestation. Background: Dystonia is heterogeneous movement…
  • MDS Virtual Congress 2021

    Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism

    L. Andreoli, M. Abbaszadeh, X. Cao, A. Cenci Nilsson (Lund, Sweden)

    Objective: We set out to compare patterns of dyskinetic behaviours induced by the systemic administration of L-DOPA and D1 or D2 receptor (D1R, D2R) agonists…
  • MDS Virtual Congress 2021

    Surround inhibition (SI) in the human motor system during real life motor tasks.

    P. Kassavetis, T. Camacho, M. Levine, M. Hallett (Bethesda, USA)

    Objective: To assess motor SI during real life motor tasks. Background: SI is a neurophysiological mechanism in the human nervous system that focuses neuronal activity…
  • MDS Virtual Congress 2020

    DystoniaNet: Neural Biomarker-Based Platform for Dystonia Diagnosis using Deep Learning

    D. Valeriani, K. Simonyan (Boston, MA, USA)

    Objective: Development and validation of a deep learning algorithmic platform for the identification of a microstructural biomarker for objective, accurate, and rapid diagnosis of dystonia.…
  • MDS Virtual Congress 2020

    Distinct maladaptive and compensatory wiring patterns in penetrant and non-penetrant dystonia mutation carriers

    A. Vo, K. Schindlbeck, N. Nguyen, A. Rommal, M. Niethammer, D. Eidelberg (Manhasset, NY, USA)

    Objective: DYT1 and DYT6 are autosomal dominant mutations for primary dystonia with incomplete penetrance. We have found that expression levels for a distinct dystonia-related functional…
  • MDS Virtual Congress 2020

    The Impact of the Sensory Trick on Gating Multimodal Afferents in Cervical Dystonia

    F. Brugger, J. Michelis, J. Walch, G. Kägi (St. Gallen, Switzerland)

    Objective: To investigate how ST modulate the postural sway in patients with idiopathic cervical dystonia (iCD) when proprioceptive and vestibular stimulation are provided simultaneously. Background: We…
  • MDS Virtual Congress 2020

    Striatal neurodegeneration in the presymptomatic phase of X-linked Dystonia-Parkinsonism

    H. Hanssen, M. Heldmann, J. Dy, J. Tantianpact, J. Steinhardt, A. Sprenger, A. Domingo, C. Reyes, R. Rosales, C. Klein, T. Münte, A. Westenberger, J. Oropilla, C. Diesta, N. Brüggemann (Luebeck, Germany)

    Objective: To identify structural brain changes in patients with X-linked dystonia-parkinsonism (XDP) and non-manifesting carriers of the TAF1 SVA retrotransposon insertion (NMC). Background: XDP is…
  • MDS Virtual Congress 2020

    Fractal analysis of muscle ultrasound imaging to evaluate muscle health and spasticity

    R. Bubnov, M. Spivak (Kyiv, Ukraine)

    Objective: The aim was to assess the capabilities of using fractal analysis of neuromuscular ultrasound images to evaluate muscle health and spasticity. Background: Ultrasound (US)…
  • MDS Virtual Congress 2020

    Characterization of pallidal neuronal activity in X-linked dystonia-parkinsonism – a model disease for compartment degeneration in the striatum

    M. Baaske, D. Rasche, C. Klein, T. Münte, C. Diesta, R. Rosales, R. Jamora, V. Tronnier, C. Moll, N. Brüggemann (Lübeck, Germany)

    Objective: Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective symptomatic therapy for dystonia in X-linked dystonia-parkinsonism (XDP). A deeper…
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