Changes In Glucose Metabolism In Essential Tremor: Within And Beyond The Cerebello-Thalamo-Cortical Circuit
Objective: To investigate differences in brain glucose metabolism between patients with essential tremor and healthy controls using [18F]FDG PET brain imaging. Background: The pathophysiological mechanisms…Essential3: An Innovative Multi-Study Phase 3 Program to Evaluate the Efficacy and Safety of Ulixacaltamide
Objective: An innovative, multi-study Phase 3 program to definitively assess safety and efficacy of ulixacaltamide in essential tremor (ET). Background: Phase 2 studies of ulixacaltamide,…Is Neuropsychological Evaluation Needed to Assess DBS Candidacy in Essential Tremor?
Objective: In this study we examined frequency of cognitive and psychiatric disorders identified during neuropsychological evaluation for Deep Brain Stimulation (DBS) in patients with Essential…Effects of Loading, Tapping Performance, and Ballistic Movements on Postural Tremor Features in Patients with Essential Tremor
Objective: To comprehensively evaluate the effects of loading, tapping performance, and ballistic movements on major tremor features in patients with essential tremor (ET). Background: In…MRgFUS thalamotomy for essential tremor: Lesion location and clinical outcomes
Objective: To examine the clinical outcomes and their relationship with patients’ baseline demographic and clinical features and lesion characteristics at 6-month follow-up in ET patients.…Relationship between postural and kinetic tremor control with VIM-DBS in Essential Tremor
Objective: To provide improved understanding of the relationship between postural and kinetic tremor presentation with deep brain stimulation (DBS) in Essential Tremor (ET). Background: ET…Subject-specific investigation of pathways underlying therapeutic outcomes of deep brain stimulation for Essential Tremor
Objective: To relate subject-specific pathway activation models of motor thalamic deep brain stimulation (DBS) to clinical outcomes in patients with Essential Tremor (ET). Background: Computational…Double-blind, randomized, crossover clinical trial to compare VIM vs PSA deep brain stimulation in patients with disabling essential tremor. Preliminary results.
Objective: To compare the safety, efficacy, energy efficiency and quality of life (QoL) outcomes of bilateral PSA-DBS vs bilateral VIM-DBS in the treatment of refractory…Patient experiences in essential tremor: mapping functional impacts to existing measures using qualitative research
Objective: To understand patient experience in essential tremor (ET), describe meaningful concepts related to treatment benefit, and compare concepts to existing clinical outcome assessments (COAs).…Focused ultrasound as rescue treatment of essential tremor after deep brain stimulation.
Objective: To describe a case of disabling essential tremor (ET) treated with unilateral MRI-Guided Focused Ultrasound (FUS) thalamotomy as rescue treatment after deep brain stimulation…
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