Dentato-Rubro-Thalamic Tract Deep Brain Stimualtion for Essential Tremor: Stimulation Parameters and Clinical Outcomes
Objective: To assess the stimulation parameters and 2-year clinical outcomes of deep brain stimulation (DBS) of the dentato-rubro-thalamic tract (DRTt) for the treatment of essential…Changes In Glucose Metabolism In Essential Tremor: Within And Beyond The Cerebello-Thalamo-Cortical Circuit
Objective: To investigate differences in brain glucose metabolism between patients with essential tremor and healthy controls using [18F]FDG PET brain imaging. Background: The pathophysiological mechanisms…Essential3: An Innovative Multi-Study Phase 3 Program to Evaluate the Efficacy and Safety of Ulixacaltamide
Objective: An innovative, multi-study Phase 3 program to definitively assess safety and efficacy of ulixacaltamide in essential tremor (ET). Background: Phase 2 studies of ulixacaltamide,…Is Neuropsychological Evaluation Needed to Assess DBS Candidacy in Essential Tremor?
Objective: In this study we examined frequency of cognitive and psychiatric disorders identified during neuropsychological evaluation for Deep Brain Stimulation (DBS) in patients with Essential…Effects of Loading, Tapping Performance, and Ballistic Movements on Postural Tremor Features in Patients with Essential Tremor
Objective: To comprehensively evaluate the effects of loading, tapping performance, and ballistic movements on major tremor features in patients with essential tremor (ET). Background: In…MRgFUS thalamotomy for essential tremor: Lesion location and clinical outcomes
Objective: To examine the clinical outcomes and their relationship with patients’ baseline demographic and clinical features and lesion characteristics at 6-month follow-up in ET patients.…Essential Tremor: The Relationship Between Hand Dominance and Tremor Severity by MVPA
Objective: The objective of this study was to analyze task-based functional Magnetic Resonance Imaging (task-fMRI) to investigate neural activity patterns in individuals diagnosed with Essential…Using LEAD-DBS to Identify the Optimal DBS Electrode in the Abbott Infinity System
Objective: To determine whether the optimal electrode contact selected in Abbott deep brain stimulation (DBS) leads is the same using conventional versus image-guided programming (LEAD-DBS…A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of OnabotulinumtoxinA for the Treatment of Upper Limb Essential Tremor: ELATE Trial
Objective: Here, we present the eligibility criteria and study design of ELATE, a Phase 2b clinical trial evaluating the safety and efficacy of onabotA compared…Is essential tremor-plus phenotype a prodromal phase of Parkinson’s disease ?
Objective: To study the probability of conversion of essential tremor (ET) and ET-plus patients to Parkinson's disease (PD). Background: ET-plus syndrome represents a wide spectrum…
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