Treatment Patterns in Essential Tremor: Real-World Evidence from Germany
Objective: To investigate the treatment patterns (TP), healthcare resource utilization (HCRU), and costs of essential tremor (ET) in a real-world setting in Germany using insurance…Beyond Memory:A Brain Health Awareness Kit for Spanish-speaking Communities
Objective: To develop an interactive workshop in Spanish that provides basic information about brain health and its importance so that community members can identify risk…Real-World Clinical and Safety Outcomes from a Prospective, Multicenter Deep Brain Stimulation Registry of Essential Tremor Patients
Objective: Here, we evaluate on-going registry outcomes derived from patients implanted with directional Deep Brain Stimulation systems with Multiple Independent Current Control (MICC) technology for…Suvecaltamide Metabolites Are CaV3 Modulators and Contribute to Pharmacological Effect
Objective: To determine the potency-concentration relationships and combined pharmacological effects for suvecaltamide and its 2 active metabolites (JZZ05000034=M01, JZZ05000035=M02; total active moiety [TAM]). Background: T-type…Classification of Tremor and Myoclonus: An Explainable Machine Learning Approach
Objective: Providing a proof of concept for the classification of movement disorders using explainable machine learning applied to power spectra derived from accelerometry recordings. Background:…Increasing access to Deep Brain Stimulation for an underserved patient population: A retrospective cohort from an urban hospital in a diverse county in the USA.
Objective: To understand whether the presence of a Bilingual Movement Disorder specialist increases access to Deep Brain Stimulation (DBS) for an underserved patient population. Background:…Impact on quality of life and nonmotor symptoms of unilateral magnetic resonance-guided focused ultrasounds (FUS) thalamotomy in patients with essential tremor.
Objective: To describe the impact on quality of life (QoL) and nonmotor symptoms of unilateral magnetic resonance-guided focused ultrasounds (FUS) thalamotomy in patients with refractory…Contribution to Efficacy by Active Metabolites of Suvecaltamide in a Preclinical Rat Model of Essential Tremor
Objective: Present the pharmacokinetic/pharmacodynamic (PK/PD) relationship and contribution to anti-tremor efficacy for suvecaltamide and its active metabolites (JZZ05000034=M01, JZZ05000035=M02) in a harmaline-induced rat model of…Age of Onset and Choice of First-line Therapy in Essential Tremor Patients
Objective: The purpose of this study is to examine the effect of age of onset on the selection of initial medication for symptomatic management of…Anosognosia for hardware-related complications in deep brain stimulation
Objective: In this series, we report two rare cases of selective unawareness to hardware-related complications in deep brain stimulation (DBS). Background: DBS has shown good…
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