Classification of Parkinson’s disease using AI based on multi-modal brain MRI connectomics
Objective: To develop a novel artificial intelligence (AI) model using connectivity matrices derived from multi-modal brain magnetic resonance imaging (MRI) to aid diagnosis and subtyping…Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder
Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…Functional Connectivity Changes Associated with Interlimb Coordination Force Deficits in Parkinson’s Disease
Objective: To investigate differences in the functional connectivity of motor regions between individuals with and without Parkinson’s disease (PD) during a force task requiring coordination…Differences in regional activity levels between healthy controls, PD-nFOG, and PD-FOG as measured by ALFF and fALFF using resting-state fMRI.
Objective: To elucidate regional neural activity differences in patients with PD-FOG using resting-state fMRI (rs-fMRI). Background: Freezing of gait (FOG) in Parkinson's disease (PD0 is…Altered Dynamic Functional Connectivity in Parkinson’s Disease Individuals with Visual Hallucinations and Dysfunction
Objective: Parkinson’s disease (PD) is frequently accompanied by visual disturbances (VD) and visual hallucinations (VH). This study aimed to analyze the alterations of Dynamic Functional…Comparative Study of Whole-Brain Functional Connectivity Patterns in Parkinson’s Disease and Essential Tremor: A Resting-State fMRI Study
Objective: Our study aimed to analyze the alterations in brain FC in subjects with tremor-dominant PD compared to ET subjects. Background: While both tremor-dominant Parkinson’s…Brain functional state mapping in resting state and network alteration in Spinocerebellar Ataxia Type 2 in comparison with healthy controls
Objective: The aim of this study is to map the brain functional network alterations by estimating functional connectivity of brain structures in spinocerebellar ataxia type 2.…Longitudinal changes in brain networks associated with clinical symptoms in idiopathic rapid eye movement sleep behavior disorder
Objective: We aimed to assess changes in brain functional networks and accompanying symptoms over years in patients with idiopathic rapid eye movement sleep behavior disorder…Metabolic connectivity assessed by dynamic FDG-fPET acquisition in Parkinson’s disease: a multimodal fPET and fMRI study
Objective: To examine the spatial convergence of hemodynamic and metabolic network characteristics based on dynamic [18F]FDG-fPET acquisition Background: While fMRI reveals within-subject hemodynamics, [18F]FDG-PET traditionally…Cognitive flexibility associates with atrophy and disrupted connectivity of the cognitive cerebellum in degenerative cerebellar ataxia
Objective: This study was to investigate the features of cognitive flexibility in patients with degenerative cerebellar ataxia, and to identify the pathophysiological correlates of cognitive…
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