Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
Objective: In this study we aim to elucidate the role of Kif5b motor subunit in the nigrostriatal pathway. We have generated different conditional knockout mice…Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…Effect of levodopa on fronto-parietal network connectivity in freezing of gait in Parkinson’s disease
Objective: To investigate the effect of levodopa on fronto-parietal network (FPN) functional connectivity (FC) in Parkinson’s disease patients with (PD-FOG) and without freezing of gait…Predictors of freezing of gait in newly diagnosed Parkinson’s disease: Clinical, dopamine transporter imaging and CSF markers in the PPMI cohort
Objective: To examine whether clinical, dopamine transporter (DAT) imaging and cerebrospinal fluid (CSF) markers can be used to predict the later development of FOG individually…Functional Balance and Neuromuscular Strength Difficulties Like Fracture Predictors in a Parkinsonian Population
Objective: To evaluate the strength and function of the hip flexor muscles and knee extensors of elderly patients with Parkinson's disease (PD) to know possible…Motor and Non-motor Features Predict Freezing of Gait in Parkinson’s Disease
Objective: To investigate and evaluate behavioral predictors of conversion to Freezing of Gait in Parkinson’s Disease (PD). Background: Freezing of Gait (FOG) has devastating consequences…Vascular parkinsonism: Clinical features and comparison with Parkinson’s disease
Objective: To define the clinical features of vascular parkinsonism (VP) and compare it to idiopathic Parkinson’s disease (iPD). Background: The main differential diagnosis of VP…Longitudinal study of freezing of gait in patients with Parkinson’s disease
Objective: We conducted a prospective hospital based cohort study to investigate the incidence of Freezing of gait (FOG) and variables associated with onset of FOG…Incidence and characteristics of gait dysfunction after subthalamic nucleus deep brain stimulation
Objective: To identify the effects of subthalamic nucleus deep brain stimulation on gait kinematics in patients with PD and describe the incidence of gait dysfunction…Assessment of gait dysfunction in patients with Parkinson’s disease and REM behavioral disorder
Objective: To determine if Parkinson's disease patients with REM behavioral disorder (RBD) have worse gait abnormalities and freezing of gait when compared to those without…
