Nucleotide repeats as genetic risk factors in a Swedish Parkinson’s disease cohort
Objective: To search for abnormal NRE in the following genes: ATXN2, ATXN3, CACNA1A, TBP, c9orf72, PRNP, POLG1A and TOMM40 in a Swedish PD cohort. Background:…Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
Objective: In this study we aim to elucidate the role of Kif5b motor subunit in the nigrostriatal pathway. We have generated different conditional knockout mice…Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…Longitudinal study of freezing of gait in patients with Parkinson’s disease
Objective: We conducted a prospective hospital based cohort study to investigate the incidence of Freezing of gait (FOG) and variables associated with onset of FOG…Incidence and characteristics of gait dysfunction after subthalamic nucleus deep brain stimulation
Objective: To identify the effects of subthalamic nucleus deep brain stimulation on gait kinematics in patients with PD and describe the incidence of gait dysfunction…Assessment of gait dysfunction in patients with Parkinson’s disease and REM behavioral disorder
Objective: To determine if Parkinson's disease patients with REM behavioral disorder (RBD) have worse gait abnormalities and freezing of gait when compared to those without…Bing-Neel syndrome presenting with Parkinsonian features: A case report
Objective: To report a case of Bing-Neel Syndrome presenting with parkinsonism. Background: A 68 year old man presented with an 18 month history of stooped…PSP and HIV: Causality or coincidence?
Objective: Our aim was to describe the clinical picture of an HIV patient with a progressive neurodegenerative disorder likely Progressive supranuclear palsy (PSP). Background: Movement…Zolpidem ameliorates the freezing of gait in a patient with PAGF (pure akinesia with freezing of gait)-the possible neural mechanism
Objective: To investigate the possible mechanism of amelioration of freezing of gait (FOG) in a patient with PAGF (Pure Akinesia with Freezing of Gait) by…Anosmia predicts development of more severe motor symptoms including freezing of gait and impaired balance at 2 year follow-up in PD
Objective: To investigate the relationship between baseline anosmia and 2-yr interval development of motor impairments in Parkinson's disease (PD). Background: More severe olfactory deficits have…
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