Characterization of gastrointestinal dysfunction in Parkinson’s by disease stage
Objective: To conduct a comprehensive cross-sectional and longitudinal characterization of gastrointestinal dysfunction (GID) in Parkinson’s disease (PD). Background: GID is an important feature of PD…Molecular alterations and pathological remodeling of colonic wall in patients with Parkinson’s disease
Objective: To evaluate, in an integrated manner, changes in faecal microbiota composition, morpho-functional alterations of the colonic mucosal barrier and changes of inflammatory markers in…Medically refractory Graves’ disease presenting as chorea and carbohydrate hyperphagia in a Kenyan adolescent
Objective: To report a unique case of adolescent-onset autoimmune hyperthyroidism presenting with chorea and carbohydrate hyperphagia (CH). Background: Autoimmune hyperthyroidism [Graves’ disease (GD)] can cause…Terminal Choking in Parkinson’s Disease
Objective: To establish whether choking is a frequent cause of death in Parkinson’s Disease (PD), if this is a feared consequence of PD in patients/caregivers…Celiac disease-related antibodies in Parkinson’s Disease patients: a case control study.
Objective: To compare anti-transglutaminase and antigliadin antibodies between Parkinson’s disease patients and healthy controls. A detailed gastrointestinal symptom investigation was studied and compared between patient…Fecal Calprotectin in Parkinson’s Disease and Multiple System Atrophy
Objective: To investigate the levels of fecal calprotectin (a marker of intestinal inflammation), in patients with Parkinson's Disease (PD) and multiple system atrophy (MSA) compared…GASTROINTESTINAL SYMPTOMS ARE ASSOCIATED WITH LEFT PREDOMINANT DOPAMINE TRANSPORTER BINDING DEFICIT IN PARKINSON´S DISEASE
Objective: To assess correlations between functional gastrointestinal (GI) symptoms and nigrostriatal dopamine transporter imaging asymmetry in Parkinson´s disease (PD) patients. Based on a theory that…Functional Constipation in Parkinson’s Disease
Objective: To analyze and compare the Rome IV Criteria of Functional Constipation between PD and HC, with that followed by MDS-NMS, intended for determining clinical…A53T-SNCA-BAC transgenic mouse exhibits multiple prodromal symptoms of Parkinson’s disease: Gastrointestinal dysfunction, hyposmia and RBD-like behavior.
Objective: To develop biomarkers and disease-modifying therapies for Parkinson’s disease, an animal model that recapitulates the early phase of the disease is indispensable. The aim…Evidence of gut dysbiosis in treatment-naïve de novo Parkinson’s disease
Objective: To determine the gut microbiome composition of treatment-naïve de novo Parkinson’s disease (PD) patients. Background: Over fifteen studies have independently demonstrated gut dysbiosis in…
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