Evidence of gut dysbiosis in treatment-naïve de novo Parkinson’s disease
Objective: To determine the gut microbiome composition of treatment-naïve de novo Parkinson’s disease (PD) patients. Background: Over fifteen studies have independently demonstrated gut dysbiosis in…The Gastrointestinal Dysfunction Scale – Parkinson’s Disease (GIDS-PD): a new tool to assess gastrointestinal dysfunction in Parkinson’s Disease
Objective: Objective: To develop and validate the Gastrointestinal Dysfunction Scale – Parkinson’s Disease (GIDS-PD), a self-report scale designed to assess presence and severity of Gastrointestinal…Effect of Lactobacillus casei supplementation on clinical response, gut microbiota and faecal metabolites in patients with Parkinson’s disease: A randomized, double-blind, placebo-controlled trial
Objective: To evaluate the effect of Lactobacillus casei strain Shirota (LcS) supplementation on symptoms, gut microbiota and faecal metabolites in patients with Parkinson's disease (PD).…Microbiome from Parkinson’s patients shows an increase in polyamines metabolism and differentially expresses microbial bacterial taxa compared to aged-matched normal controls
Objective: The goal of this study was to determine whether the microbiome from Parkinson’s disease (PD) has alterations in a) Polyamine metabolism and b) Expressed…The Gut Dysmotility Questionnaire (GDQ) for Parkinson’s disease: current development
Objective: To develop a questionnaire to screen for and monitor gastrointestinal symptoms in patients with Parkinson’s disease (PD), entitled Gut Dysmotility Questionnaire (GDQ). Background: Gut…Changes in fecal microbiota composition in patients with Huntington’s disease in China
Objective: Gut-brain axis has been associated with multiple brain disorders [1,2,3]. This study is to explore fecal microbiota changes in Huntington's disease (HD). Background: Huntington's…miRNA sequencing from routine colonic biopsies reveals an enrichment of submucosal hsa-miRNA-486-5p in Parkinson’s disease
Objective: In the present work, we aimed to investigate the expression of microRNAs (miRNAs) in routine colonic biopsies obtained from patients with idiopathic Parkinson's disease…Deposition of phosphorylated α-synuclein in the muscularis externa of the gastrointestinal tract in patients with prodromal Parkinson’s disease
Objective: In the present study, we investigated Lewy pathology in the enteric nervous system (ENS) of seven Parkinson’s disease (PD) patients who underwent a gastrectomy,…Sex-related disease differences in Parkinson’s disease
Objective: To highlight differences in clinical disease parameters between sexes in a cohort of Parkinson’s disease (PD) patients. Background: PD is a progressive neurodegenerative disorder…Dietary insights of Parkinson’s Disease patients
Objective: To report on the patterns of nutritional intake in an Australian Parkinson’s disease (PD) cohort. Background: There is limited information about the dietary habits…
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