The role of the gut microbial dysbiosis and serum inflammatory profile for the discrimination of clinical subtypes in Parkinson’s disease
Objective: To investigate whether clinical phenotypes can be predicted by the assessment of gut microbiome and serum inflammatory profile of PD patients. Background: Recent evidence…The relationship between constipation and alteration of gut microbiota in patients with Parkinson’s disease
Objective: To study compositional and functional differences in the gut microbiota and its products between individuals with PD and matched controls,and these differences are or…Treatment of Levodopa Dose Failure with Subcutaneous Apomorphine Injection
Objective: We evaluated a subset of patients who were enrolled in the AMIMPAKT trial of sc apomorphine injection to treat morning akinesia (see reference) who…Non-Motor Symptom In Young Onset Parkinson Disease as a Cause of Pharmacoresistence In Epilepsy
Objective: To report an interesting initial presentation of PD causing refractory epilepsy. Background: A lady with refractory depression, presented with first seizure at age 42,…Characterization of the gastrointestinal dysfunction in mice overexpressing the human mutation (A53T) of alpha-synuclein
Objective: The aim of this study was to determine if mice overexpressing the human mutation of alpha-synuclein develop gastrointestinal (GI) dysfunction, and to understand the…Evaluation of the Effect of STN-DBS on the Gastrointestinal Symptoms in Patients with Parkinson’s Disease via GIQLI
Objective: Our aim is to evaluate the effects of Subthalamic Nucleus (STN)-DBS on the quality of life in PD patients by using the Gastrointestinal Quality…The Prevalence of Gastrointestinal Symptoms in Parkinson’s Disease Patients in Bethesda Hospital, Yogyakarta, Indonesia
Objective: We were conducting the research to determine the prevalence of the gastrointestinal symptoms in Parkinson's disease patients in Bethesda Hospital, Yogyakarta, Indonesia, by using…Early gastrointestinal dysfunction is predictive of faster progression in Parkinson’s disease
Objective: To evaluate whether constipation at time of diagnosis has prognostic significance in terms of motor and cognitive progression in PD. Background: There is evidence…Smooth muscle dysfunction in the gastrointestinal system in the 6-OHDA model of Parkinson´s Disease
Objective: To explore the connection between the central dopamine system and the autonomous nervous system in GI dysfunction in PD, using animal models. Background: Gastrointestinal…Gastrointestinal Symptoms and Enteric Nerve Dysfunction in A53T Mice
Objective: To investigate the relationship between α synucleinopathy-induced enteric neuropathy and gastrointestinal dysfunction in A53T mice. Background: Approximately 80-90% of PD patients suffer from GI…
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