Differential glial and neuronal response in Lipopolysaccharide induced Parkinson’s disease model: Modulation with Apocyanin and Curcumin
Objective: To understand the differential susceptibility of neuronal and glial populations to lipopolysaccharide (LPS) mediated insult in an animal model of PD. Also, to test…Neuroprotection effects of probiotics strains on a chronic MPTP-induced mouse model of Parkinson’s disease
Objective: To explore the effects of probiotics strains on the neuroinflammation and degeneration of dopaminergic neurons in chronic Parkinson’s disease (PD) mice model. Background: Microglia-mediated…Lycopene ameliorates haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation
Objective: The study was undertakento investigate the role of striatal neurotransmitters and neuroinflammatory cytokines in the neuroprotective effect of lycopene against haloperidol induced orofacial dyskinesia…Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Cerebrospinal Fluid C-Reactive Protein
Objective: In this study, we intended to investigate the association between severity of PD motor symptoms and the cerebrospinal fluid (CSF) levels of CRP using…Combined administration of A2A receptor antagonist and 5-HT1A/1B receptor agonist reverses neuroinflammation in the 6-OHDA model of Parkinson’s disease
Objective: To investigate whether in a model of Parkinson's Disease (PD), an early treatment with the serotonin 5-HT1A/1B receptor agonist eltoprazine and the adenosine A2A…A post-mortem and in vivo study of neuroinflammation and Toll like-receptors in Parkinson’s disease
Objective: To investigate inflammatory change and Toll-like receptor (TLR) expression in human post-mortem Parkinson’s disease (PD) brains and to test the efficacy of TLR-blocking agents…Reduction of neuroinflammation by selective inhibition of the N-type calcium channel is beneficial in various animal models of neurodegeneration, here in the SOD1G93A transgenic mouse model of ALS
Objective: Neuroinflammation is a pathological hallmark of several neurodegenerative diseases. We speculated that reduction of calcium ion influx specifically in neurons should reduce inflammatory cellular…Antibodies to alpha-Synuclein in Parkinson disease
Objective: Alpha-synuclein (α-syn) plays a very important role in pathogenesis of Parkinson’s disease (PD). There are enough evidence of neuroinflammation in the brain tissue of…Cerebrospinal fluid levels of cytokines in multiple system atrophy: A cross-sectional study of the atalan msa registry (CMSAR)
Objective: To compare the cerebrospinal fluid (CSF) levels of 38 cytokines in multiple system atrophy (MSA) patients vs. control and Parkinson’s disease (PD) subjects. Background:…Neutrophil to lymphocyte ratio, lymphocyte to monocyte ratio and Parkinson’s Disease: Preliminary report
Objective: We conducted a pilot study to determine the association between the neutrophil to lymphocyte ratio (NLR), he lymphocyte to monocyte ratio (LMR), the levels…
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