MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Inflammation"

  • 2019 International Congress

    Occurrence of brain capillary dysfunction in patients with REM sleep behavior disorder

    S. Eskildsen, A. Iranzo, M. Stokholm, K. Stær, K. østergaard, M. Eroles, M. Otto, K. Svendsen, A. Pla, D. Vilas, P. Borghammer, J. Santamaria, A. Møller, C. Gaig, D. Brooks, E. Tolosa, L. østergaard, N. Pavese (Aarhus N, Denmark)

    Objective: To assess whether changes in brain capillary function measured with magnetic resonance imaging (MRI) can be detected in patients with REM sleep behavior disorder…
  • 2019 International Congress

    Balance training modulates the concentration of pro- and anti-inflammatory cytokines in the plasma of elder people and PD patients. A pilot study

    J. Szymura, J. Kubica, M. Więcek, J. Pera (Krakow, Poland)

    Objective: Assessment as to whether moderate intensity systematic balance training (BT) affects the level of IL-10, IL-6 and TNF-α in healthy, elder people and in…
  • 2019 International Congress

    18F-DPA714 PET reveals neuroinflammatory activity in the Substantia nigra of patients with Parkinson disease

    S. Lavisse, C. Wimberley, S. Goutal, M. Bottlaender, B. Kuhnast, MA. Peyronneau, M. Sarazin, P. Hantraye, C. Thiriez, P. Remy (Fontenay Aux Roses, France)

    Objective: We investigated whether 18F-DPA714 imaging could be a sensitive marker of neuroinflammation in Parkinson disease (PD). We took into account the polymorphism of TSPO…
  • 2019 International Congress

    Inflammatory cytokines in Saudi Parkinson cohort

    N. Alsomali, E. Al-Ofi, M. Obaid, A. Alrafiah (Riyadh, Saudi Arabia)

    Objective: To identify inflammatory diagnostic and prognostic biomarkers for PD in serum. Background: Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's…
  • 2019 International Congress

    Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder

    K. Stær, A. Iranzo, M. Stokholm, K. østergaard, M. Eroles, M. Otto, K. Svendsen, A. Pla, D. Vilas, J. Santamaria, A. Møller, C. Gaig, P. Borghammer, D. Brooks, E. Tolosa, N. Pavese (Aarhus N, Denmark)

    Objective: To explore possible correlations between levels of microglial activation (neuroinflammation) in the Substantia Innominata (SI), the major source of cholinergic input to the cortex,…
  • 2018 International Congress

    Nanoscale imaging reveals disorganization of the brain extracellular space in Lewy body-injected mice

    F. Soria, N. Danne, C. Paviolo, E. Doudnikoff, B. Dehay, L. Groc, L. Cognet, E. Bezard (Bordeaux, France)

    Objective: To explore the brain extracellular space and its matrix at a nanometric scale in a context of α-synuclein-induced neurodegeneration. Background: The extracellular space (ECS)…
  • 2018 International Congress

    Tetrahydroisoquinoline Molecule Identified in Traditional Ayurveda Medicine Modulates Inflammation in MPTP Mice

    R. Banerjee, R. Paidi, P. Jaisankar, K. Mohanakumar, S. Biswas (Kolkata, India)

    Objective: Potential ‘Anti-parkinsonian’ activity of a tetrahydroisoquinoline (TIQ) molecule of traditional ‘Ayurveda’ medicine was tested in a preclinical MPTP mice model for Parkinson’s disease (PD).…
  • 2018 International Congress

    Molecular immunological action and epigenetic modification of the human papillomavirus vaccination and associated neuropsychiatric side effects

    N. Kanzato, K. Nakachi, Y. Takahashi (Okinawa, Japan)

    Objective: To investigate the clinical manifestations of neuropsychiatric side effects after the Human papillomavirus (HPV) vaccine, and to investigate the immunological actions and epigenetic modification.…
  • 2018 International Congress

    T lymphocytes in Parkinson’s disease pathogenesis and therapy: A systematic review

    J. Baird, J. Quinn (Portland, OR, USA)

    Objective: A systematic literature review was conducted to synthesize the current state of knowledge on the role of T lymphocytes in Parkinson’s disease (PD) pathology…
  • 2018 International Congress

    Dopaminergic impairments following repeated exposure to stress on the neurotoxicity of lambda-cyhalothrin through inflammatory cytokines in rats

    R. Shukla, R. Gupta, S. Goel, A. Pant, V. Khanna (Bhopal, India)

    Objective: Impact of psychological stressors in modulating the toxicity of environmental chemicals has been suggested, however the mechanism this is not clear. Background: Repeated stress…
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