Effectiveness and micro-electrodes findings of deep brain stimulation of the STN via a parietal approach in post-infectious previously implanted Parkinson´s patients
Objective: To report our experience with an alternative entry point to access STN in the treatment of Parkinson's disease (PD) and its micro-electrodes findings. Background:…The effects of viral priming on neurotoxin induced neurodegeneration and synapse dysfunction in cell culture models relevant to Parkinson’s disease
Objective: To investigate the effects of viral innate immune activation on neurodegeneration and synaptic protein expression in dopaminergic (DA)-like neurons following treatment with Parkinson's disease…Treatment of lipopolysaccharide-induced parkinsonism
Objective: This single case report of levodopa-responsive parkinsonism, caused by an accidental systemic contamination with 10 microgram lipopolysaccharides (LPS) from Salmonella minnesota, describes the treatment…DJ-1 regulates intracellular signaling in a highly cell type specific manner
Objective: To evaluate a cell type specific action of DJ-1, a PD and cancer associated gene, in intracellular signaling pathways. Background: Understanding the pathophysiology of…Targeting TLR4 for disease modification in multiple system atrophy: Experimental evidence
Objective: To assess the efficacy of toll-like receptor 4(TLR4) agonists to ameliorate the functional and neuropathological phenotype of a transgenic mouse model of multiple system…Lrrk2 alleles modify host response to microbial infections
Objective: The mechanisms by which allelic changes in LRRK2 modulate the susceptibility to Parkinson's disease, Crohn's disease and leprosy remain unknown. We hypothesized that leucine-rich…Progression of microglial activation and neuroinflammatory responses in a transgenic mouse model of multiple system atrophy
Objective: Our aim was to characterize the progression of microglial activation during disease progression in a transgenic mouse model of multiple system atrophy (MSA). Background:…Apocyanin ameliorates post-stroke movement disorder in rats: Possible role of neurochemical and inflammatory alterations
Objective: To study the neuroprotective efficacy of apocynin, a NADPH oxidase inhibitor in 1) alterations of post- stroke motor behaviour, 2) alterations of various neurotransmitter…
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