Melatonin Modulates NLRP3 Inflammasome Activation through TLR2 to Protect Against Parkinson’s Disease
Objective: This study aims to investigate the impact of MLT on inflammation signaling pathway mediated by TLR2 in α-synuclein (α-syn) overexpressed BV2 cells and PD…Peripheral immunity and clinical phenotypes in patients with ventriculomegaly
Objective: To characterize the neutrophil-to-lymphocyte ratio (NLR) levels in the peripheral blood of patients with ventriculomegaly and its correlation with clinical outcomes Background: Ventriculomegaly is…Exercise Mitigates DNA Methylation Changes at cg17274742 Associated with the Circadian Gene Variant PER2 rs2304672: A Biobank Analysis
Objective: This research aims to dissect the influence of physical activity and circadian rhythms on neuroinflammation and neurodegenerative disease progression, focusing on Parkinson's Disease (PD).…Immunomodulatory Effects Of Covid-19 Vaccination On Inflammatory And Neurotrophic Factors In Parkinson’s Disease: Insights From Clinical Subtypes
Objective: This study investigates the impact of COVID-19 vaccination on levels of interleukin 6 (IL-6) and brain-derived neurotrophic factor (BDNF) in patients with Parkinson's disease…Single cell transcriptomics of peripheral blood mononuclear cells and associations with clinical outcomes in Parkinson’s disease
Objective: To assess transcriptomics signatures for monocytes and T-cells in different stages of Parkinson’s disease (PD) compared to controls and possible correlations with clinical outcomes.…Characterization of Autoimmune Parkinsonism. A case series
Objective: To report the presentation features in autoimmune parkinsonism in a neurological reference center in Arequipa Peru. Background: Epidemiological studies suggest that a rare association…Insulin-like growth factor 2 and inflammatory response in Parkinson Disease: Potential predictor marker
Objective: Clinical diagnosis Parkinson's disease (PD), is often difficult, with the appearance of motor symptoms hence the importance of identify non-invasive early markers is a…Mitigating The Impact Of Covid-19 On Parkinson’s Disease: Insights From Vaccination Strategies
Objective: This study aimed to investigate the impact of COVID-19 infection on patients with Parkinson's disease (PD), comparing those who received COVID-19 vaccines and those…Age and Parkinson’s disease: clinical and biomarkers profiling of younger and older patients
Objective: Given the well-known clinical differences and natural history of Parkinson's disease (PD) according ot patients age, wthis study aims at exploring the different pathophysiological…TRPV1: A Potential Therapeutic Target for Inflammation and Pain in Parkinson’s Disease
Objective: Unveiling the Pain Mechanism in Parkinson's Disease: A Path to New Therapies Background: Parkinson's disease (PD) are well-known movement disorder. While motor symptoms are…
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