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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Levodopa(L-dopa)"

  • MDS Virtual Congress 2021

    Subcutaneous Levodopa Infusion for Parkinson’s disease Patients with Motor Fluctuations: Open-Label Efficacy Outcomes from the BeyoND study

    W. Poewe, F. Stocchi, L. Adar, R. Case, T. Yardeni, A. Espay (Innsbruck, Austria)

    Objective: To review one-year exploratory efficacy data from the ND0612 BeyoND study. Background: ND0612 is an investigational subcutaneous delivery system providing minimally invasive, continuous infusion…
  • MDS Virtual Congress 2021

    Limitations of conventional dopaminergic medication in advanced Parkinson’s disease: results from 127 patients treated with Levodopa Carbidopa Intestinal Gel

    J. Szász, V. Constantin, K. Orban-Kiss, L. Bancu, D. Georgescu, J. Szederjesi, M. Ciorba, A. Racz, I. Mihaly, K. Kelemen, S. Szatmari (Targu Mures, Romania)

    Objective: To evaluate the characteristics of the last conventional dopaminergic treatments in a large cohort of patients with advanced Parkinson’s Disease (APD) treated with Levodopa…
  • MDS Virtual Congress 2021

    Cellular Modeling of Tyrosine Hydroxylase Deficiency Recapitulates Patient Phenotypes and Response to Treatment.

    A. Tristán-Noguero, I. Fernández-Carassa, C. Bermejo-Casadesús, C. Calatayud, L. Campa, F. Artigas, R. Domingo-Jiménez, M. Pineda, S. Alcántara, A. Raya, R. Artuch, A. García-Cazorla, A. Consiglio (Esplugues de Llobregat, Spain)

    Objective: Characterize a new cellular model of Tyrosine Hydroxylase deficiency (THD) based on induced pluripotent stem cells (iPSCs) to better understand the pathophysiology and test…
  • MDS Virtual Congress 2021

    CVT-301 (levodopa inhalation powder) improves Patient Global Impression of Change (PGIC) over 1 year in patients with Parkinson’s disease (PD): a meta-analysis

    M. Saint-Hilaire, A. Corbin, P. Zhao, D. Kegler-Ebo (Boston, USA)

    Objective: A meta-analysis of PGIC results was performed using combined data from 3 different studies of CVT-301 in patients with PD over a total of…
  • MDS Virtual Congress 2021

    Predictive factors of LCIG infusion therapy adherence – a single-center study of 103 consecutive LCIG patients

    V. Viljaharju, T. Mertsalmi, KAM. Pauls, M. Koivu, J. Eerola-Rautio, M. Udd, E. Pekkonen (Helsinki, Finland)

    Objective: The objectives of this study were to find predictive factors for early dropout from levodopa-carbidopa intestinal gel (LCIG) infusion in advanced Parkinson’s disease (PD)…
  • MDS Virtual Congress 2021

    Effects of freezing gait and medication on postural control during prolonged standing in individuals with Parkinson’s disease

    L. Cupertino, CR. de Souza, CN. de Oliveira, R. Treza, SM. Hondo, E. Los Angeles, C. Bernardo, MJ. Carvalho, DB. Coelho (Sp, Brazil)

    Objective: To analyze the effects of freezing of gait (FoG) and medication on postural adjustments during prolonged standing in individuals with Parkinson's disease (PD). Background:…
  • MDS Virtual Congress 2021

    CLE-600: Treating nocturnal and early morning OFF symptomology in Parkinson’s disease with the OLAR® platform

    E. Berkovich (Petch-Tikva, Israel)

    Objective: Development of a treatment for nocturnal and early morning OFF symptomology in Parkinson’s disease. Background: Levodopa Parkinson’s disease (PD) treatment is limited by its…
  • MDS Virtual Congress 2021

    Levodopa responsive gait dynamics in ON- and OFF-state freezing of gait in Parkinson’s disease

    T. Virmani, L. Pillai, A. Glover, R. Landes (Little Rock, USA)

    Objective: To determine which spatiotemporal gait parameters respond to levodopa in Parkinson’s patients with levodopa ON- and OFF-state gait freezing. Background: Levodopa-ON-state gait freezing is…
  • MDS Virtual Congress 2021

    Deep brain stimulation in Parkinson’s disease

    S. Laassila, N. Chtaou (Fez, Morocco)

    Objective: Study the various clinical, electrophysiological and therapeutic parameters of operated patients. Evaluate the effectiveness of deep brain stimulation of STN in Parkinson's disease. Background:…
  • MDS Virtual Congress 2021

    Validation of a real- time monitoring system to detect motor symptoms in patients with Parkinson´s disease treated with Levodopa Carbidopa Intestinal Gel

    A. Bougea, M. Palkopoulou, S. Pantinaki, A. Antonoglou, E. Efthymiopoulou (Athens, Greece)

    Objective: Our aim was to analyze the ability of system to combine information on OFF periods, falls and dyskinesias of patients with PD. Background: Levodopa…
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