Pharmacokinetics of Levodopa in patients with Parkinson’s disease: Efforts toward a predictive model
Objective: Our aim was to explore correlations between the pharmacokinetics of levodopa (LD) and clinical manifestation in patients with Parkinson’s disease (PD). Our goal was…PF-QII Analysis of Deep Brain Stimulation versus Levodopa-carbidopa Intestinal Gel: Real-world Differences in Patient Characteristics and Quality of Life Outcomes
Objective: To evaluate differences in demographics, disease characteristics, quality of life (QOL), and caregiver burden (CB) between deep brain stimulation (DBS) and levodopa-carbidopa intestinal gel…Temporal properties of resting-state functional MRI are associated with ON/OFF levodopa MDS-UPDRS III scores in patients with Parkinson’s disease
Objective: To explore the relationship between temporal resting-state functional magnetic resonance imaging (fMRI) properties and ON/OFF Levodopa motor performance scores in patients with Parkinson's disease…Daily Time-Course of Efficacy of Continuous Subcutaneous Infusion of Foslevodopa/foscarbidopa in Advanced Parkinson’s Disease Patients from a Phase 1b Study
Objective: Characterize and compare the time-course of Parkinson’s disease (PD) symptoms following 24h/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa and oral levodopa/carbidopa (LD/CD). Background: As…The influence of ANNK1/DRD2 haplotypes on the onset of complications of long-term levodopa therapy in Parkinson’s disease
Objective: To investigate an influence of selected polymorphisms in DRD2 and ANKK1 genes on the occurrence of complications of long-term levodopa therapy in Serbian PD…Technology-based therapy response and prognostic biomarkers in Parkinson’s disease: results from a prospective evaluation of a de novo PD patients’ cohort
Objective: To prospectively evaluate motor performances with technology-based objective measures (TOMs) in a cohort of PD patients in order to identify therapy response and prognostic…Motor, non-motor and cognitive correlates of carotid intima-media thickness in patients with Parkinson’s disease
Objective: To determine the correlation of carotid intima-media thickness (IMT) to motor, non-motor and cognitive scales in patients with Parkinson’s disease (PD). Background: Increased IMT…Real-World Data on the Use of Levodopa-Carbidopa Intestinal Gel in Patients with Advanced Parkinson’s Disease who are Treated with Deep Brain Stimulation: The PD-DUAL Study
Objective: To examine the use of oral anti-parkinsonian medications in advanced Parkinson’s disease (APD) patients who have a history of, or current treatment with deep…High levodopa plasma concentration in the acute levodopa challenge test predicts levodopa-induced dyskinesia in Parkinson’s disease
Objective: We aimed to investigate the correlation between levodopa pharmacokinetics and levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD). Background: In patients with PD, pulsatile dopaminergic…Loss of Weight Associated with Levodopa / Carbidopa Intestinal Gel
Objective: To define the prevalence and severity of WL in patients of the Movement Disorders Unit of our center treated with LCIG and to analyze…
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