Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD
Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…DBS for PD in Albania
Objective: DBS: surgical procedure of choice for PD. Albanian experience. Background: Parkinson disease (PD) : the decrease of dopamine’s levels because of nigro – striatal…Biphasic Dyskinesias in Parkinson’s disease Patients treated with Levodopa/Carbidopa Intestinal Gel: Insights from a Multicenter Retrospective Analysis
Objective: We aimed to characterize Parkinson's disease (PD) patients who developed the onset of new troublesome dyskinesias after Levodopa-Carbidopa Intestinal Gel (LCIG) initiation. We were…Safinamide reduces membrane excitability and synaptic transmission of striatal spiny projection neurons in a rat model of Parkinson’s disease
Objective: The effect of safinamide (saf) on the electrical membrane properties and both excitatory and inhibitory synaptic transmission of striatal spiny projection neurons (SPNs) was…Availability of levodopa and clinicopathological features of patients with multiple system atrophy
Objective: To investigate the availability of levodopa for pathologically confirmed multiple system atrophy (MSA) patients and determine the clinicopathological features of levodopa responders with MSA.…Continuous levodopa- carbidopa gel recovers motor cortex plasticity in advanced Parkinson’s disease
Objective: The objective of this study was to investigate if continuous infusion of levodopa- carbidopa gel (LCIG) improves motor complications of Parkinson's disease (PD) and…Opposing effects of levodopa on basal ganglia activity in Parkinson’s disease during motion and rest
Objective: To explore the pattern of activation within the motor network during the movement and resting phases of the tapping task in Parkinson’s disease (PD)…Gastrointestinal symptoms as a risk factor for the appearance of motor fluctuations in patients with advanced Parkinson disease
Objective: Gastrointestinal alterations in patients with Parkinson`s Disease (EP) provoke alterations in the absorption of levodopa that facilitates the development of motor fluctuations. Study the…Impact of repeated oral administration of Opicapone on the plasma pharmacokinetics of levodopa
Objective: To examine the inhibitory effect of COMT on the plasma pharmacokinetics of levodopa resulting from repeated, once daily, oral administration of an Opicapone (OPC)…The effect of ADORA2A gene polymorphism on the dyskinesia of Parkinson’s Disease
Objective: To investigate the relationship of levodopa-induced dyskinesia with ADORA2A gene polymorphisms in PD patients. Background: With the progression of the disease, motor complications and…
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