MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Levodopa(L-dopa)"

  • 2016 International Congress

    Multidisciplinary Parkinson rehabilitation in the Netherlands: The effectiveness of points of Parkinson (POP)

    E.T. Steendam-Oldekamp, W.A.W.F. Rutgers, T. van Laar (Groningen, Netherlands)

    Objective: To analyze the effect of the POP rehab program for advanced PD patients on motor- and non-motor symptoms up to 2 years and determine…
  • 2016 International Congress

    Levodopa-entacapone-carbidopa intestinal gel in Parkinson’s disease – A randomized, crossover infusion study

    M. Senek, D. Nyholm (Uppsala, Sweden)

    Objective: To compare the systemic levodopa exposure during administration of levodopa-entacapone-carbidopa (LECIG) intestinal gel with levodopa-carbidopa intestinal gel (LCIG) in advanced Parkinson's disease (PD) patients.…
  • 2016 International Congress

    Continuous subcutaneous delivery of solubilized carbidopa improves the pharmacokinetic profile of levodopa

    R. Shaltiel-Karyo, E. Zawoznik, I. Weinstock, M. Nemas, Y. Caraco, P.A. LeWitt, S. Oren, O. Yacoby-Zeevi (Rehovot, Israel)

    Objective: To characterize the peripheral pharmacokinetics and CNS metabolism of levodopa during continuous subcutaneous delivery of solubilized carbidopa. Background: Although many commercial levodopa formulations include…
  • 2016 International Congress

    Biseptol a new antiParkinsonian agent?

    K. Karpinska, V. Smolanka (Uzhgorod, Ukraine)

    Objective: To evaluate the possible effect of combined intake of levodopa/carbidopa and trimethoprim/sulfamethoxazole on the duration of ON/OFF periods in a PD patient. Background: Drug…
  • 2016 International Congress

    Quantitative assessment of advanced therapies in Parkinson’s disease using the Parkinson kinetigraph (PKG)

    R.L. Blaze, J. Tan, A.H. Evans (Parkville, Australia)

    Objective: Our aim was to establish whether objective measurements using the Parkinson's Kinetigraph can detect differences between patients undergoing different advanced therapy with either deep…
  • 2016 International Congress

    Effectiveness of Levodopa responsiveness of Blink reflex recovery: An objective method to differentiate Parkinsonian syndromes

    C. Gaddipati, M. Umaiorubahan, C.U. Velmurugendran, V. Shankar (Chennai, India)

    Objective: We attempted to find an objective tool by assessing the variability of levodopa induced change in the blink reflex recovery to differentiate Parkinsonian syndromes.…
  • 2016 International Congress

    AntiParkinsonian treatment patterns and motor complications among patients with Parkinson´s disease in Estonia

    L. Kadastik-Eerme, N. Taba, P. Taba (Tartu, Estonia)

    Objective: To evaluate pharmacological treatment patterns in patients with Parkinson´s disease (PD), prevalence of motor complications, and factors associated with them. Background: Levodopa is the…
  • 2016 International Congress

    Motor fluctuations in relation to plasma concentrations following a single-dose of levodopa/carbidopa microtablets in advanced Parkinson’s disease

    M. Senek, H. Askmark, S.M. Aquilonius, F. Bergquist, R. Constantinescu, A. Ericsson, S. Lycke, A. Medvedev, M. Memedi, F. Ohlsson, J. Spira, J. Westin, D. Nyholm (Uppsala, Sweden)

    Objective: The aim of this study was to characterize the levodopa and carbidopa plasma concentration in relation to blinded motor function ratings. This is a…
  • 2016 International Congress

    Patient experiences following Parkinson’s disease treatment with inhaled levodopa: Results from a Phase 2b study

    P. LeWitt, A. Niyazov, A. Sedkov, H. Murck, A. Guo (West Bloomfield, MI, USA)

    Objective: To report patient experiences from a clinical trial investigating Parkinson's disease (PD) control following treatment with inhaled levodopa. Background: CVT-301, an inhaled levodopa powder…
  • 2016 International Congress

    Efficacy and safety of a L-dopa delivery and monitoring medical device

    Y.G. Tirat-Gefen (Fairfax, VA, USA)

    Objective: The objective of this study is to evaluate algorithms in a medical device for l-dopa delivery and monitoring. This wearable medical device will measure…
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