Deficient Balance Mechanisms during Walking in People with Parkinson’s Disease
Objective: Investigate whether people with Parkinson’s disease (PD) have deficient balance mechanisms following visual perturbations during walking. Background: We recently showed that maintaining upright balance…Rhythmic activity of subthalamic neurons during externally and internally generated movements in Parkinson’s disease
Objective: To find the specificity of neuronal responses in the subthalamic nucleus during externally and internally generated voluntary movements in Parkinson’s disease. Background: The motor…Rhythmic movements decompose in Parkinson’s disease with worse disease severity at low frequencies: akinesia or impaired ability to move more slowly than comfortable?
Objective: To explore the relationship between disease severity, minimum comfortable velocity and dwell time in Parkinson's disease. Background: People find it hard to move smoothly…Motor onset of Parkinsonʼs disease: Is there a somatotopic pattern?
Objective: To study the clinical onset and progression of motor manifestations in different body regions in early PD patients. Background: The vulnerability of the nigrostriatal…Real Time Quality Control for Subjective Endpoints in Clinical Trials
Objective: Here we present a system which is capable of performing nearly-real time monitoring of UPDRS part-3 motor assessments using a combination of multidimensional statistics…A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AKST4290 in Subjects with Parkinson’s Disease on Stable Dopaminergic Treatment (TEAL Study)
Objective: Assessment of efficacy and safety in subjects with Parkinson’s disease (PD) following treatment for 12 weeks with placebo or AKST4290, a highly specific and…Comparing the effects of rosemary and selegiline on behavioral symptoms of Parkinson’s animal model in mice
Objective: Parkinson is from common disorders of central nervous system and the second disease in neurodegenerative diseases which occurs in 1% of people over the…Use of Figurative Language in Describing OFF Periods in Parkinson’s Disease
Objective: To explore the use of figurative language by individuals with Parkinson’s disease (PD) describing their experience during OFF periods. Background: OFF periods are characterized…Kinematic control in children with essential tremor
Objective: We aim to explore motor control in children with essential tremor (ET) utilizing the Kinarm exoskeleton robot. Background: Tremor is one of the most…A sensor-based analysis of freezing of turning in bed: A new manifestation of nocturnal hypokinesia
Objective: To identify characteristics of freezing of turning in bed in PD patients using an axial inertial sensor (NIGHT-Recorder®) and synchronous video recording. Background: Freezing…
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