The development of an electronic motor symptoms diary for Parkinson’s disease using qualitative patient insights
Objective: To develop an electronic version of the Hauser diary, commonly used in clinical trials to assess motor fluctuations and dyskinesia in patients with Parkinson’s…A non-linear index can detect early postural instability in people with Parkinson’s disease: Enhancing perspectives on the utilization of cost-effective technologies.
Objective: To investigate the effectiveness of a non-linear index for identifying the decline in postural control associated with PD progression. Background: Postural instability is a…Benefits of Exercise on Mobility, Balance, and Cognition in Community-Dwelling Older Adults: An On-Land vs. In-Water Comparison Study
Objective: We conducted a three-arm trial (water exercise group × land exercise group × no exercise group) to assess the effects of a 4-month exercise…Continuous Monitoring of Hypomimia in Parkinson’s disease using a Sensor-equipped Cap
Objective: We propose an e-textile in form of a cap to continuously track hypomimia in Parkinson’s disease (PD) allowing for an unobtrusive monitoring of facial…Assessing a Video Based Approach at Measuring Parkinson’s Disease Severity – A Validation Study
Objective: To validate the Parkinson’s remote interactive monitoring system’s assessment of Parkinson’s disease compared to a clinical assessment completed by a movement disorder specialist. Background:…Wearable sensors and AI in Parkinson’s disease – How continuous symptom and treatment response monitoring can enable better clinical decision making – Interim results from an observational study
Objective: To investigate how continuous objective information on motor symptoms and treatment response combined with subjective patient reported insights can be used to optimize Parkinson’s…Boosting Clinical Trial Power in Parkinson’s Disease with AI-Generated Digital Twins
Objective: To evaluate the incorporation of prognostic digital twins to enhance traditional clinical trials in Parkinson’s Disease (PD) for disease modifying therapies. We assess the…Remote monitoring of upper limb function in Huntington’s disease using a wearable sensor
Objective: To develop and evaluate machine learning models to identify patients with Huntington's disease (HD) and to predict their symptom severity related to upper limb…Long-Term Evolution of Advanced Parkinson’s Disease Burden: Subgroup Analysis from the 24 Month International PROSPECT Observational Study
Objective: To evaluate the long-term evolution of clinical outcomes and treatment patterns in people with advanced Parkinson’s disease (PwaPD) whose symptoms are inadequately controlled by…Three-Year Progression of the Postural Control Alterations in Hereditary Spastic Paraplegias
Objective: To assess the progression of postural control impairments in patients with HSP and identify the most sensitive COP parameter to change during a three-year…
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