Motor decision-making in Parkinson’s disease
Objective: The aim of this study is to test motor decision-making ability in Parkinson's disease (PD) in conditions with different biomechanical properties and levels of…Detecting Parkinson’s Disease from body limb acceleration using machine learning and a frequency-domain analysis
Objective: To test whether the acceleration frequency of different body parts during gait can reveal characteristic patterns of Parkinson’s Disease (PD). The technical aim was…Effect of KW-6356, a novel adenosine A2A receptor antagonist/inverse agonist, on motor and non-motor symptoms in Parkinson’s disease patients as an adjunct to levodopa therapy: Results of Phase 2b study
Objective: To evaluate the efficacy and safety of KW-6356 in Parkinson’s disease (PD) patients with levodopa therapy, irrespective of the presence of wearing-off (WO). Background:…Dopaminergic modulation of express reaching responses in Parkinson’s disease
Objective: This study investigates the role of dopamine (DA) in modulation of automatic stimulus-driven responses. We investigated the effect of PD, DA medication, and instruction…Deficient interhemispheric connectivity underlies movement irregularities in Parkinson’s disease
Objective: The aim of this study was to investigate whether impaired execution of drawing spirals relates to deteriorations in interregional connectivity. Background: Movement execution is…Emotional stress exacerbates parkinsonian resting tremor
Objective: To examine the role emotions may play in modulating the characteristics of parkinsonian resting tremor. Background: There is ample evidence showing cognitive stress can…Movement vigor is differentially encoded in motor cortex and globus pallidus in Parkinson disease
Objective: To test the hypothesis that pallidocortical local field potential (LFP) beta oscillations encode movement vigor. Background: Recent work suggests the motor basal ganglia adjusts…Beta synchronization of the subthalamic nucleus during self-initiated and externally generated movement in parkinsonian patients in OFF and ON states
Objective: The aim of this study is to estimate the level of beta synchronization of the subthalamic nucleus (STN) evoked by internally and externally generated…Influence of Levodopa on Archimedes Spiral Drawings in Idiopathic Parkinson’s Disease
Objective: To study the effects of levodopa on Archimedes spiral drawings by idiopathic Parkinson’s Disease (PD) patients. Background: Handwriting difficulty can develop as an early…IS FATIGUE ASSOCIATED WITH BALANCE IN PARKINSON’S DISEASE?
Objective: The aims of this study were to verify the correlation between fatigue and balance in individuals with PD; to compare balance in individuals with…
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