Modulation of thalamocortical network dynamics via deep brain stimulation in humans with Tourette syndrome
Objective: To (1) investigate the impact on thalamocortical network dynamics in response to low frequency and high frequency deep brain stimulation and (2) uncover the…Improving drug discovery using brain oscillations as biomarkers of Parkinson’s disease
Objective: The aim of this study was to assess the use of cortical oscillations as translational biomarkers for drug development for the motor symptoms of…Structural and functional signature of primary orthostatic tremor
Objective: (1) We aimed to characterize, in primary orthostatic tremor (OT), the structural and functional defects in the cerebellar motor pathways; (2) We correlated the…Cortical grey matter atrophy in the motor system in Friedreich ataxia: The IMAGE-FRDA study
Objective: To examine the anatomical integrity of the motor cortex in Friedreich ataxia (FRDA). Background: FRDA is an inherited neurodegenerative disorder characterised by progressive gait…Early grey matter changes in structural covariance networks in Huntington’s disease
Objective: To identify network integrity changes in Huntington's disease (HD) using grey matter whole brain structural covariance networks and to examine relationships between anatomical networks…Pronounced beta oscillations are a characteristic of the cortico-basal ganglia loop of subacute and chronic animal models of Parkinson´s disease
Objective: To compare the power spectral densities of local field potentials recorded from the cortico-basal ganglia loop of a subacute (reserpine) and a chronic (6-OHDA)…Impaired cerebellum to motor cortex associative plasticity in Parkinson’s disease
Objective: To compare the corticocortical paired associative stimulation (PAS)-induced spike-timing dependent plasticity (STDP)-like plasticity between Parkinson's disease (PD) and healthy elder subjects. Background: Patients with…Botulinum toxin treatment of freezing of gait in Parkinson’s disease patients as reflected in functional magnetic resonance imaging of leg movement
Objective: To reflect botulinum toxin treatment of freezing of gait in Parkinson´s disease patients in functional magnetic resonance imaging of leg movement. Background: Freezing of…Pain-motor integration in the primary motor cortex in Parkinson’s disease
Objective: To investigate pain-motor integration experimentally in patients with Parkinson's disease (PD), with and without chronic pain. Background: Although chronic pain is a common non-motor…Pallidal DBS and pallidotomy alter cortical synchronization in Parkinson’s disease
Objective: To investigate electrophysiologic characteristics of sensorimotor cortical activity in patients with Parkinson's disease (PD) undergoing globus pallidus deep brain stimulation (GPi DBS) or radiofrequency…
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