MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Pathophysiology"

  • MDS Virtual Congress 2020

    CHCHD2 mRNA levels in erythrocyte are reduced in patients with multiple system atrophy

    G.l Liu, X.d Liu, T. Feng (Beijing, China)

    Objective: To investigate CHCHD2 mRNA expression of erythrocyte in patients with multiple system atrophy (MSA). Background: Coiled-coil-helix-coiledcoil-helix domain containing 2 (CHCHD2) are reported to be associate with…
  • MDS Virtual Congress 2020

    Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study

    M. Meyer, I. Sibon, F. Lamarre, J. Asselineau, A. Foubert-Samier, J. Mazère, A. Delamarre, O. Rascol, A. Pavy-Le Traon, F. Tison, P. Fernandez, W. Meissner (Bordeaux, France)

    Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…
  • MDS Virtual Congress 2020

    GCI-induced neurodegeneration and synucleinopathy in non-human primates

    M. Teil, S. Dovero, M.L Artocarena, M. Bourdenx, G. Porras, B. Mollenhauer, M.T Herrero, M. Vila, J. Obeso, B. Dehay, E. Bezard (Bordeaux, France)

    Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…
  • 2019 International Congress

    Increased lysosphingolipids levels in blood of patients with multiple system atrophy

    K. Senkevich, G. Baydakova, A. Emelyanov, M. Nikolaev, A. Kopytova, I. Miliukhina, E. Gracheva, A. Kudrevatykh, I. Krasakov, L. Khublarova, I. Fursova, Y. Irishina, N. Zalutskaya, Y. Beltseva, E. Zakharova, S. Pchelina (Saint-Petersburg, Russian Federation)

    Objective: To estimate activity of lysosomal enzymes and lysosphingolipids concentration in dry blood spot of patients with synuleinopathies: Parkinson’s disease (PD), dementia with Lewy bodies…
  • 2019 International Congress

    Hypothalamic functional connectivity correlates with autonomic symptom burden in patients with Multiple System Atrophy

    M. Sklerov, N. Browner, D. Drazheva, E. Dayan (Chapel Hill, NC, USA)

    Objective: To investigate the association between autonomic symptom burden and hypothalamic functional connectivity in patients with MSA. Background: Multiple system atrophy (MSA) is a progressive…
  • 2019 International Congress

    Pain in patients with multiple system atrophy: a pain-related evoked potential study

    M. Takeda, F. Okada, H. Tachibana, S. Kasama, H. Yoshikawa (Nishinomiya, Japan)

    Objective: The purpose of this study was to investigate the pathophysiology of pain in patients with multiple system atrophy (MSA). Background: MSA is an atypical…
  • 2019 International Congress

    Vocal cords electromyography abnormalities in multiple system atrophy phenotypes: relevance for the pathophysiology of stridor

    M. Todisco, E. Alfonsi, I. Isaias, R. Zangaglia, B. Minafra, M. Terzaghi, N. Pozzi, C. Pacchetti (Pavia, Italy)

    Objective: To define correlations between vocal cords electromyography (EMG) abnormalities and stridor in multiple system atrophy (MSA) phenotypes. Background: MSA is a rare α-synucleinopathy characterized…
  • 2019 International Congress

    Widespread distribution and abundant accumulation of alpha-synuclein oligomers in multiple system atrophy brain

    H. Sekiya, H. Kowa, H. Koga, M. Takata, W. Satake, N. Futamura, I. Funakawa, K. Jinnai, M. Kanagawa, K. Kobayashi, T. Toda (Kobe, Japan)

    Objective: To examine the distribution of alpha-synuclein (αSyn) oligomers as an early pathological change in multiple system atrophy (MSA) brains. Background: Although severe neuronal loss…
  • 2019 International Congress

    Multiple System Atrophy – perspectives in diagnosis?

    P. Alster, D. Koziorowski, L. Królicki, A. Friedman (Warsaw, Poland)

    Objective: The aim of this study was to study the role of perfusion single photon emission computed tomography (SPECT) in the examination of multiple system…
  • 2019 International Congress

    Abnormal respiratory rate and patterns in MSA

    E. Driver-Dunckley, B. Goodman (Scottsdale, AZ, USA)

    Objective: To evaluate respiratory rate and patterns in patients with Multiple Systems Atrophy (MSA). Background: One of the primary clinical features of multiple system atrophy…
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