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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Treatment"

  • MDS Virtual Congress 2020

    Inosine 5′-Monophosphate to Raise the Serum Uric Acid Level in Patients with Multiple System Atrophy (IMPROVE-MSA study): A Multi-center, Randomized, Double Blind, Placebo-controlled, Parallel Assigned Clinical Trial

    J.J Lee, J.H Yoon, S.J Kim, H.S Yoo, S.J Chung, Y.H Lee, S.Y Kang, H.W Shin, S.K Song, J.Y Hong, M.K Sunwoo, J.E Lee, J.S Baik, Y.H Sohn, P.H Lee (Goyang-si, Republic of Korea)

    Objective: To investigate the safety, tolerability, and capability of serum uric acid (UA) elevation of inosine 5'-monophosphate (IMP) in multiple system atrophy (MSA). Background: Converging…
  • MDS Virtual Congress 2020

    Body Weight-Supported Treadmill Training Improves Walking Function in Multiple System Atrophy: A Case Report

    R. Hand, C. Testa (Richmond, VA, USA)

    Objective: Multiple system atrophy (MSA) is a rapidly progressive synucleinopathy involving autonomic dysfunction and impaired mobility. MSA has been further sub-classified into two phenotypes: parkinsonian…
  • MDS Virtual Congress 2020

    Treatment of Neurogenic Orthostatic Hypotension (nOH) in Multiple System Atrophy (MSA) with a wearable Pneumatic Compression Garment utilising Soft Robotics

    N. Sawal, H. Singh, A. Beri (Chandigarh, India)

    Objective: To use a novel Pneumatic Garment device for treatment of nOH in MSA. Background: nOH is present in 66-90% of patients with MSA and…
  • MDS Virtual Congress 2020

    Cardiac Safety of PBT434, an Inhibitor of Alpha-Synuclein Aggregation for the Treatment of Multiple System Atrophy (MSA)

    D. Stamler, M. Bradbury, C. Wong, E. Offman (Newark, CA, USA)

    Objective: Evaluate potential cardiac liability of PBT434 using concentration-response and outlier analyses of ECG and pharmacokinetic (PK) data from a Phase 1 study of PBT434…
  • MDS Virtual Congress 2020

    Physical Therapy Role with Differential Diagonosis and Treatment with Dizziness and Multiple System Atrophy: A Case Study

    J. Liu (Sacramento, CA, USA)

    Objective: The purpose of this case study is to address the role of physical therapy (PT) in a case of complex dizziness, progressive symptoms, and…
  • 2019 International Congress

    Considerations before initiating therapy in Parkinsonism: basing on the health-related quality of life.

    FT. Liu, J. Wang (Shanghai, China)

    Objective: We aimed to compare the determinants of life quality between drug naïve PD and MSA-P patients. Background: To improve the quality of life (QoL)…
  • 2019 International Congress

    High Content Screening of synucleinopathy in primary cortical neurons : dissecting out the interplay between the basic synuclein pools

    F. de Giorgi, E. Bezard, F. Ichas (Bordeaux, France)

    Objective: To set up a robust (see ref 1 for definition)  96-well High Content Screening assay of synucleinopathy in primary cultures of cortical neurons. Background:…
  • 2019 International Congress

    Continuous dopaminergic treatment with levodopa/carbidopa intestinal gel in multiple system atrophy: report of three patients

    S. Delalic, S. Ibrulj, N. Zupancic, D. Flisar, M. Trost, Z. Pirtosek, M. Kojovic (Ljubljana, Slovenia)

    Objective: To evaluate the effect of continuous dopaminergic treatment with levodopa/carbidopa intestinal gel (LCID) on motor and non-motor symptoms in multiple system atrophy (MSA) patients.…
  • 2019 International Congress

    Preferred place of death (PPOD) in PD, PSP and MSA

    C. Morris, R. Walker, M. Lee, J. Adamson (Newcastle, United Kingdom)

    Objective: To ascertain whether people with PD, PSP and MSA have a PPOD Background: Achieving a PPOD is felt to be an important factor in…
  • 2019 International Congress

    Is safinamide helpful in multiple system atrophy?

    R. Simões, A. Gonçalves, JJ. Ferreira (Lisboa, Portugal)

    Objective: To retrospectively review the clinical benefit of safinamide in patients with Multiple System Atrophy. Background: Safinamide is a new monoamine oxidase-B inhibitor, with dopaminergic…
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