Relationship of MDS-UPDRS non-motor symptoms to cognitive functioning in patients with Parkinson’s disease
Objective: To evaluate the relationship among individual items from the MDS-UPDRS Part I and measures of cognitive functioning in patients with PD. Background: Non-motor symptoms…Psychiatric manifestations in the initial motor stage of Parkinson’s disease
Objective: To estimate the prevalence and correlates of neuropsychiatric symptoms (NPS) in a cohort of consecutive patients with Parkinson's disease (PD) recruited in the initial…A rapid chemical-genetic screen utilising impaired movement phenotypes in caenorhabditis elegans
Objective: Development of a fast and unbiased screening method to identify C. elegans mutants with movement disabilities and drugs to improve impaired locomotion. Background: Identifying…The neurosteroid dehydroepiandrosterone sulfate (DHEAS) reverses the dopaminergic deficiencies in mild hepatic encephalopathy: A possible therapeutic issue for the management of parkinsonism in cirrhotic patients
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…Sensorimotor impairments and the excitability of spinal cord in lead intoxicated rat during development and a potent restorative effect of curcumin
Objective: In this study we firstly investigated the effect of prenatal exposure of rats to lead (3g/l) from neonatal to adult age, on the motor/sensory…Amelioration of αLPHA-synuclein aggregation and motor behavior deficits by apocyanin in intranigral lipopolysaccharide induced animal model of Parkinson’s disease
Objective: The present study evaluated the therapeutic potentials of apocyanin for the treatment of neurobehavioral consequences in LPS induced PD model. Background: Parkinson's disease (PD),…Influence of treadmill gait training with additional load on motor function, postural instability and history of falls for individuals with Parkinson’s disease: A randomized clinical trial
Objective: The objective of this study was to evaluate the effects of additional load (5% and 10%) with treadmill gait training on the overall motor…Voice harmonic amplitude differences before and after LSVT LOUDTM in Parkinson’s disease
Objective: To evaluate voice harmonic amplitudes from acoustic spectra of speech produced by subjects with Parkinson's disease (PD) before and after voice treatment, in order…Copper chelation efficacy of alginate/chitosan based D-penicillamine nanoparticles in rat model of non-Wilsonian brain copper toxicosis
Objective: To evaluate the copper (Cu) chelation efficacy of orally administered D-penicillamine loaded nanoparticles to that of conventional D-penicillamine therapy for 90 days in Wistar…
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