Study on association between physical and genetics role in essential tremor – A case control study
Objective: To elucidate the relationships between physical and genetics parameters in essential tremor patients and controls. Tremor is an involuntary, rhythmic shaking of any part…Differential expression of cerebral dopamine neurotrophic factor (CDNF) in the hippocampus and in the striatum of LRRK-2 mutant rat model of Parkinson’s disease
Objective: The objective of our study was to characterize the behavioral phenotype of the transgenic LRRK-2 rat in the context of PD model and to…Psychosis in Huntington’s disease
Objective: To describe the characteristics and phenomenology of psychotic symptoms in a Spanish cohort of HD patients. Background: Neuropsychiatric features are characteristic symptoms in Huntington's…EARLYSTIM: STN-DBS alleviates behavioural side effects of dopamine replacement therapy when compared to best medical treatment
Objective: To compare effects of STN-DBS and dopamine replacement therapy (DRT) on behaviour in PD in a 2 year follow-up study. Background: A large panel…Relationship of MDS-UPDRS non-motor symptoms to cognitive functioning in patients with Parkinson’s disease
Objective: To evaluate the relationship among individual items from the MDS-UPDRS Part I and measures of cognitive functioning in patients with PD. Background: Non-motor symptoms…Psychiatric manifestations in the initial motor stage of Parkinson’s disease
Objective: To estimate the prevalence and correlates of neuropsychiatric symptoms (NPS) in a cohort of consecutive patients with Parkinson's disease (PD) recruited in the initial…A rapid chemical-genetic screen utilising impaired movement phenotypes in caenorhabditis elegans
Objective: Development of a fast and unbiased screening method to identify C. elegans mutants with movement disabilities and drugs to improve impaired locomotion. Background: Identifying…The neurosteroid dehydroepiandrosterone sulfate (DHEAS) reverses the dopaminergic deficiencies in mild hepatic encephalopathy: A possible therapeutic issue for the management of parkinsonism in cirrhotic patients
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…Sensorimotor impairments and the excitability of spinal cord in lead intoxicated rat during development and a potent restorative effect of curcumin
Objective: In this study we firstly investigated the effect of prenatal exposure of rats to lead (3g/l) from neonatal to adult age, on the motor/sensory…
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