Identification of ZYIL1, a novel NLR family pyrin domain containing 3 protein inhibitor: a potential disease modifier in Parkinson’s disorder
Objective: Identification and evaluation of the potential of a novel NLR family pyrin domain containing 3 (NLRP3) inflammasome inhibitor (ZYIL1) as a Parkinson’s disease (PD)…Novelty Seeking: A Narrative Review
Objective: To explore novelty seeking (NS) as a construct, in both its adaptive and maladaptive roles, in order to provide insight into the cognitive and…Understanding neuropsychological features of dopa responsive dystonia in children
Objective: To describe the neuropsychological features in five siblings with dopa responsive dystonia (DRD) due to autosomal dominant GCH1 related disease (AD GCH1). Background: Although…Longitudinal association of mild behavioral impairment with cognitive decline in Parkinson’s disease
Objective: To analyze the cross-sectional and longitudinal association between mild behavioral impairment and cognitive impairment in Parkinson’s disease. Background: Cognitive impairment and neuropsychiatric symptoms (NPS)…Racial and Ethnic Differences in Suicidal Ideation in North American patients with Huntington’s Disease: Analysis using the ENROLL-HD Dataset
Objective: To identify racial and ethnic differences in history of suicidal ideation among Huntington’s Disease patients, using the ENROLL-HD, 2020 periodic dataset. Background: Suicidal ideation…Modulation of autophagy and neuroinflammation by Niclosamide in MPTP Induced- Parkinson’s disease model
Objective: The current investigation aimed to investigate the neuroprotective effect of niclosamide (NI) on autophagy and neuroinflammatory pathways in Parkinson’s disease (PD). Background: Autophagy dysregulation…Cervical Dystonia as a post Wernicke’s Encephalopathy sequelae.
Objective: To highlight the rare clinical presentation of cervical dystonia(sagittal shift) as a post Wernicke’s Encephalopathy sequelae. Background: Wernicke’s encephalopathy (WE) is a neurological emergency…Can very early levodopa prevent self-injury in Lesch-Nyhan Disease?
Objective: To determine whether levodopa treatment starting at a very young age can prevent the development of the full clinical phenotype in Lesch-Nyhan disease. Background:…The impact of anxiety symptoms and treatment on Parkinson’s disease-related disability: findings from the Parkinson’s Progression Markers Initiative
Objective: To determine the functional consequences of baseline anxiety symptoms and the longer-term impact of initiation of anxiety treatment in Parkinson’s disease (PD). Background: While…The role of depression in the development of Impulse Control Disorders in Parkinson´s Disease.
Objective: We aimed to investigate whether depression is associated with a higher risk of developing impulse control disorders (ICD) in Parkinson´s disease (PD) patients and…
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