The neural correlates of apathy in premanifest and manifest Huntington’s disease: A cross-sectional multimodal imaging study
Objective: To delineate the brain correlates of apathy severity by means of glucose metabolism (18-FDG PET), grey-matter (GM) and white-matter (WM; FA-DTI) changes and relations…WILSON’S DISEASE: A Mongolian case
Objective: Objective: To determine the early clinical features that predict younger people who has Wilson’s disease(WD). Background: Backround: WD is fatal neurodegenerative disorder that is…Patient-reported hallucinations and the probability of progression to dementia in Parkinson’s disease
Objective: To evaluate the influence of neuropsychiatric symptoms in identifying Parkinson’s disease (PD) patients who will progress to dementia (PDD) in the imminent future (~4…Prospective Analysis of Morphological Markers of Development of Impulsive Compulsive Behaviors in De Novo Parkinson’s Disease
Objective: Aim of this study was to determine whether structural imaging features present at disease onset or over disease course predict the development of ICB…Psychiatric manifestations in the initial motor stage of Parkinson’s disease
Objective: To estimate the prevalence and correlates of neuropsychiatric symptoms (NPS) in a cohort of consecutive patients with Parkinson's disease (PD) recruited in the initial…A rapid chemical-genetic screen utilising impaired movement phenotypes in caenorhabditis elegans
Objective: Development of a fast and unbiased screening method to identify C. elegans mutants with movement disabilities and drugs to improve impaired locomotion. Background: Identifying…The neurosteroid dehydroepiandrosterone sulfate (DHEAS) reverses the dopaminergic deficiencies in mild hepatic encephalopathy: A possible therapeutic issue for the management of parkinsonism in cirrhotic patients
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…Sensorimotor impairments and the excitability of spinal cord in lead intoxicated rat during development and a potent restorative effect of curcumin
Objective: In this study we firstly investigated the effect of prenatal exposure of rats to lead (3g/l) from neonatal to adult age, on the motor/sensory…Amelioration of αLPHA-synuclein aggregation and motor behavior deficits by apocyanin in intranigral lipopolysaccharide induced animal model of Parkinson’s disease
Objective: The present study evaluated the therapeutic potentials of apocyanin for the treatment of neurobehavioral consequences in LPS induced PD model. Background: Parkinson's disease (PD),…Influence of treadmill gait training with additional load on motor function, postural instability and history of falls for individuals with Parkinson’s disease: A randomized clinical trial
Objective: The objective of this study was to evaluate the effects of additional load (5% and 10%) with treadmill gait training on the overall motor…
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