Nigral stimulation for the treatment of refractory gait disturbances in Parkinson’s disease
Objective: Evaluate the effect of SNr stimulation on freezing of gait and analyse changes in local field potentials. We describe an early-onset Parkinson´s disease patient…Disrupted Amplitude of Low-frequency Fluctuations and Causal Connectivity in Parkinson’s Disease with Apathy
Objective: We aimed to explore associated neural substrates changes in Parkinson’s disease (PD) with apathy via amplitude of low-frequency fluctuations (ALFF) and Granger Causality Analysis…The Impact of short in-patient rehabilitation courses for people with Parkinson´s disease
Objective: To find out whether a 10 to 14 days group-based multidisciplinary in-patient rehabilitation course for patients with Parkinson´s disease has any long-term effect on…Assessing the Quality of Economic Evaluation of Treatment Options for Parkinson’s disease Using the Quality of Health Economic Studies (QHES) Scale
Objective: The objective of this study was to critically appraise all the published evidences on the economic evaluation of treatment options for Parkinson’s disease. Background:…MRI volumetrics in parkinsonian syndromes
Objective: We aimed to explore the ability of MRI volumetrics by using an automated segmentation software called Accubrain in differentiating (1) between different parkinsonian syndromes…How well can nurses recognize motor fluctuations in Parkinson’s disease: A survey of 238 registered nurses
Objective: To evaluate awareness of the three main parkinsonian motor symptomatologies, among general nursing population. Background: One aim of Parkinson’s disease (PD) management is to…Integrated whole exome sequencing and chromosomal microarray in familial Parkinson’s disease
Objective: To determine whether whole exome sequencing (WES) plus chromosomal microarray analysis (CMA) yield a genetic etiology in a cohort of 110 individuals with familial…Increased Parkin expression in a PARK20 (SYNJ1 mutation) iPSCs-based model
Objective: To generate mechanistic insight into how the SYNJ1 p.Arg258Gln mutation leads to neurodegeneration in juvenile Parkinsonism. Background: In humans, the SYNJ1 homozygous p.Arg258Gln missense…Expanding the canvas of PARKIN mutations and clinical phenotypes in familial and early onset Parkinson’s disease patients
Objective: To identify PARKIN mutations in PD patients with familial history (FPD) and early onset PD patients with no family history (EOPD; ≤50 years) and…Early-onset Parkinson’s disease in seven patients with heterozygosity for parkin mutation
Objective: To present and discuss a series of 7 patients with early-onset Parkinson’s Disease and heterozygosity for PARK2 mutation. Background: Parkin mutation in homozygosity or…
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