Machine Learning Model using Eye Movements for the Differential Diagnosis of iPD and Atypical Parkinsonian Syndromes
Objective: To develop a machine learning (ML) model to first between differentiate between healthy controls, idiopathic PD, Atypical Parkinsonian syndromes and then further subclassify as…Heterozygous ATP7B variants in patients with parkinsonism
Objective: To describe a retrospective case series of thirteen cases carriers of heterozygous variants of the ATP7B gene manifesting with specific cases of parkinsonism. Background:…Parkinsonism Due to Delayed Neurotoxicity of CAR-T Therapy
Objective: We report a case of secondary parkinsonism due to delayed neurotoxicity induced by ciltacabtagene autoleucel (cilta-cel) chimeric antigen receptor T-cell therapy (CAR-T) as well…30-year Delayed Diagnosis of Juvenile Parkinson’s Disease in a Patient Misdiagnosed with Dopa-responsive Dystonia
Objective: To report a case of Juvenile Parkinson’s Disease (JP) misdiagnosed as dopa-responsive dystonia (DRD) and to emphasize the importance of early genetic testing in…Expanding the Spectrum of Alzheimer’s Disease Clinical Presentations: Progressive Dysarthria with Monomelic Tremor
Objective: To present an unusual clinical presentation of an atypical Corticobasilar syndrome secondary to Alzheimer's disease. Background: Corticobasilar syndrome (CBS) typically presents with motor symptoms…Specialized palliative care for advanced Parkinsonian syndromes: bridging the gap
Objective: The Advanced Care Team for Parkinson’s (ACT-PD) pilot program at the Calgary Movement Disorders Clinic aimed to bridge gaps in specialized palliative care for…Depression and Social Engagement in Community-Dwelling Older Adults with Parkinsonism
Objective: To examine how depression and gait influence social engagement in parkinsonism. Background: Depression significantly affects quality of life in parkinsonism. Yet, the interplay of social…The Impact of Anodal transcranial Direct Current Stimulation on the Metabolomic Profiles of Cerebrospinal Fluid in Parkinson’s Disease
Objective: To explore the impact of anodal transcranial direct current stimulation (tDCS) on the cerebrospinal fluid (CSF) metabolomic profile of Parkinson's disease (PD). Background: Transcranial…Facilitators and Barriers to Exercise Program Implementation in Parkinson’s Disease Rehabilitation: A Comprehensive Review Using the Consolidated Framework for Implementation Research
Objective: To systematically identify and evaluate the facilitators and barriers influencing the implementation of exercise programs in Parkinson’s disease (PD) rehabilitation using the Consolidated Framework…Striatal Dysfunction in Parkinson’s Disease Progression: A 18F-9-fluoropropyl-(+)-dihydrotetrabenazine(18F-AV133) PET Study
Objective: To investigate the patterns of striatal 18F-AV133 uptake in relation to disease progression across different stages of PD and to examine its relationship with…
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