Novel mechanistic involved in targeting Parkinsons Disease by Indolocarbazole derivatives as inhibitors against Cyclin Dependent kinases using molecular modelling and simulation approaches
Objective: To validate effect of Indolocarbazole derivatives on Cyclin dependent kinase for treating Parkinson's (Preliminary work in context of CDK5 assay and Simulations have been…Evolution of Motor and Non-Motor Manifestations in Prodromal Parkinsonism
Objective: To trace the evolution of early motor and non-motor manifestations of synculeinopathy from the stage of idiopathic REM sleep behavior disorder (iRBD) until defined…The analysis of cognitive impairment associated with Parkinson’s disease
Objective: The study was to investigate the traits, the related factors and the impact on quality of life of cognitive impairment associated with Parkinson's disease.…Olfactory impairment correlates strongly with limbic blood flow in patients with Parkinson’s disease
Objective: To examine the cerebral blood flow pattern of patients of Parkinson's disease with olfactory disorders, and to investigate the correlation between olfactory impairment and…Affective Theory of Mind Impaired in Parkinson’s Disease: Negative- and Neutral- specific impairments of Emotion State Decoding
Objective: The primary aim of this study was to investigate whether the ability to interpret positive, negative, or neutral emotion from a pair of photographed…Clinical predictors of screen-defined dementia in early Parkinson’s
Objective: Predicting early dementia in Parkinson’s disease (PD) has important implications for individual prognosis, designing clinical trials and targeting novel treatments, but there remains a…Brain Mechanisms of Associative Memory Deficits in Parkinson’s Disease without Dementia
Objective: Characterization of neural mechanisms of associative memory deficits in Parkinson’s disease (PD) without dementia (PD-non-Dementia). Background: The early presence of memory deficits in PD…Abnormal NMDA-related Electrophysiology in Parkinson Disease Dementia
Objective: Investigate mismatch negativity in Parkinson disease with dementia. Background: Parkinson’s disease with dementia (PDD) is an important cause of cognitive impairment in Parkinson’s disease…Hypometabolism of the posterior parietal cortex in PD with dementia: [18F]FDG PET study
Objective: To investigate the neuroimaging marker for dementia in Parkinson’s disease (PD) patients using [18F]FDG PET. Background: Dementia may occur in patients with PD during…Extended “Timed Up and Go”: A Clinical Indicator of Cognitive State in Parkinson’s Disease?
Objective: To evaluate an extended Timed Up and Go (extended-TUG) as a potential holistic indicator of Parkinson’s disease; hypothesised to correlate closely with disease severity…
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