Association between impulse control disorders and depression in drug-naïve Parkinson’s disease
Objective: To determine the association between depression and impulse control disorders (ICDs) in patients with Parkinson's disease (PD). Background: Depression is one of the most…Site investigator perspectives on exclusionary determinations of SWEDDs (Scans Without Evidence of Dopaminergic Deficit) during screening in the SURE-PD3 study
Objective: To assess investigators’ level of agreement with centrally adjudicated SWEDDs based on dopamine transporter imaging (qualitatively defined) during screening of subjects whom investigators had…Application of PKG System for Objective Measurement and Early Identification in Parkinson’s Disease
Objective: This study aimed to assess the correlations of the PKG data with clinical scores of bradykinesia, rigidity and tremor. Background: The treatment of levodopa…Are effects of Rock Steady Boxing and PD SAFExTM on the motor symptoms of Parkinson’s disease maintained long-term? – A single-blinded randomized controlled trial
Objective: To determine if the benefits associated with RSB and PD SAFExTM on the motor symptoms of PD wash out over time. Background: Parkinson’s disease…Postmenopausal hormone therapy and Alzheimer’s disease, dementia, and Parkinson’s disease: A systematic review and time-response meta-analysis
Objective: The study aim was to determine the relation between menopausal hormone therapy and Alzheimer's disease, dementia, and Parkinson's disease in human subjects. Background: We…Efficacy and security starting safinamide treatment with 100 mg/day in Parkinson’s disease
Objective: Evaluating the efficacy and security starting safinamide treatment with 100 mg/day in PD Background: Safinamide has a unique dopaminergic and non-dopaminergic mode of action…A Case of Improved Psychotic Depression and Motor Symptoms in Parkinson’s Disease following Electroconvulsive Therapy (ECT)
Objective: To describe a case of motoric, affective, and psychotic symptoms improving in PD following ECT. Background: Parkinson’s disease (PD) is a neurodegenerative disease caused…Glucocerebrosidase activity and atypical parkinsonism: a multi-centre exploratory study
Objective: We aimed to determine the frequency of Glucocerebrosidase (GBA) deficiency (subclinical Gaucher's Disease type 1, GD1) in patients with atypical parkinsonism (AP) with features…Atypical parkinsonism due to a mutation in the SLC9A6 gene
Objective: Expanding phenotypic spectrum in christianson syndrome (CS). Background: CS is an X-linked neurodevelopmental disorder characterized by intellectual disability combined with microcephaly, cognitive impairment, ataxia,…Simultaneous, levodopa-responsive Holmes’ tremor and hemiparkinsonism due to midbrain cavernous malformation
Objective: We report a case of concomitant Holmes’ tremor (HT) and hemiparkinsonism (HP) attributable to a single structural lesion with robust clinical response to levodopa.…
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