Ambroxol treatment of primary macrophages derived from patients with GBA-associated Parkinson’s disease
Objective: The aim was to evaluate the effectiveness of the restoration of GCase activity in macrophages from GBA-PD patients using pharmacological chaperone ambroxol. Background: Mutations…Blood–brain barrier breakdown in an adult mouse model of Parkinson’s disease
Objective: This study aims to evaluate the integrity of the blood-brain barrier (BBB) in parkinsonism. Background: Parkinson's disease (PD) is a neurodegenerative disorder which is…Prospective Characterization of Genetically Confirmed X-linked Dystonia Parkinsonism Patients and their Families: A 1 year longitudinal feasibility study
Objective: A one year feasibility study for a planned prospective longitudinal study of X-linked Dystonia-Parkinsonism patients and their families in rural Philippines. Background: X-linked dystonia…How Parkinson’s Disease Affects Value-Based Decisions
Objective: Parkinson’s Disease (PD) is a degenerative motor disease that causes subtle deficits in decision-making as a result of striatal dysfunction due to dopamine depletion.…Impulse Control Disorders in a Brazilian population with Parkinson´s disease -an observational study
Objective: To Analyse Impulse Control Disorders (ICDs) and Related Behaviors (RB) in 36 Brazilian patients with Parkinson´s disease (PD) and compare the cognition of the…Semantic Memory Assessment in Parkinson’s Disease
Objective: We assessed the performance of patients with a diagnosis of Parkinson’s disease (PD) in a series of semantic memory (SM) tasks including both living…Task difficulty and the three-stimulus oddball task in patients with PD
Objective: Examine the effect of task difficulty on event-related potentials (ERPs) in an oddball task in patients with PD. Background: In three-stimulus oddball tasks, some…The contribution of striatal dopamine to feedforward motor control during gait initiation in Parkinson’s disease
Objective: To establish the contribution of striatal dopamine to gait initiation in Parkinson’s disease. Background: Gait initiation (GI) is characterized by anticipatory postural adjustments (APAs),…Experimental model of developing of Parkinson’s disease
Objective: Analyzing the reserpine model of Parkinsonian syndrome Background: There are several experimental models of Parkinson's disease: reserpine, methamphetamine, 6-hydroxydopamine (6-OHDA), 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine - substances that…Antipsychotics Use in Parkinson’s Disease and Mortality Risks
Objective: To describe the use of antipsychotics in patients with Parkinson’s disease (PD) and study its associated mortality risks. Background: The US Food and Drug…
- « Previous Page
- 1
- …
- 142
- 143
- 144
- 145
- 146
- …
- 405
- Next Page »