Constipation with selected prodromal features increases risk of subsequent Parkinson’s Disease
Objective: To use the electronic medical record (EMR) to understand the independent and joint effects of constipation and other prodromal features on the risk of…Genomic variants associated with cognitive impairment in Parkinson’s disease: Ethnicity-specific GWAS
Objective: We aimed to identify the genomic variants that are associated with cognitive impairment in patients with Parkinson’s disease (PD). Background: Cognitive impairment is an…Long-Term Effects of LPS and Alcohol in Rats: A Model of Neuro-Degenerative Disease
Objective: We postulate alterations of the intestinal barrier (or leaky guts) enhances inflammation, as well as the production of alpga (α)-synuclein which has characteristic pathological…Swallowing assessment in Parkinson’s Disease using Dynamic Magnetic Resonance Imaging (dMRI)
Objective: To evaluate any dysphagia-signs in Parkinson’s disease (PD) with technique that is non-invasive, without-radiation-exposure and gives good soft-tissue contrast. Background: Swallowing, a basic oromotor…Metabolic syndrome and insulin resistance in Parkinson’s disease: could they affect motor or cognitive symptoms?
Objective: The objective of this work was to detect the markers of metabolic syndrome and insulin resistance in patients with PD and to study their…Non-motor symptoms and risk of functional dependency in early Parkinson’s disease
Objective: To determine whether non-motor symptoms predict the development of functional dependency in Parkinson’s disease (PD). Background: Non-motor symptoms are increasingly recognized as an integral…Cognitive dysfunction in patients with Parkinson’s disease and psychosis
Objective: The objective of this study was to explore the pattern of cognitive dysfunction in the patient's with Parkinson's disease and psychosis (PD-P) by comparing…Automated Metabolic Pattern Analysis in the Differential Diagnosis of Parkinsonism in a Swedish Cohort
Objective: To assess the accuracy of an automated, disease-specific, pattern model to distinguish among PD, MSA and PSP, in comparison with the final clinical diagnosis.…Investigating the cellular role of LRRK2 in the immune system
Objective: The objective of this project is to investigate the effect of Leucine Rich-Repeat Kinase 2 (LRRK2) dysfunction in the signalling mechanisms in macrophages and…The effect of baseline cognitive status of Parkinson’s disease on the outcome after deep brain stimulation surgery
Objective: To evaluate the effect of baseline cognitive status of Parkinson’s disease (PD) on the outcome after deep brain stimulation (DBS) surgery. Background: Advanced dementia…
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