Structural connectivity changes in prodromal Parkinson’s disease patients: a multimodal MRI study
Objective: We hypothesised that changes in the brain structure and connectivity would be present at this stage. Background: There is wide consensus that prolonged prodromal…Functional mobility tests and their relationship with disease stage in patients with Parkinson’s Disease
Objective: The main objective of this study is set as to determine the relationship between several Functional Mobility Tests (FMT) and disease stages in patients…Measuring progression of nigrostriatal degeneration in Parkinson’s disease using 18F-AV-133 vesicular monoamine transporter type-2 (VMAT2) PET
Objective: To evaluate the progression of nigrostriatal degeneration in participants with Parkinson’s disease (PD) using 18F-AV-133 vesicular monoamine transporter type-2 (VMAT2) PET. Background: Vesicular monoamine…Ambroxol treatment of primary macrophages derived from patients with GBA-associated Parkinson’s disease
Objective: The aim was to evaluate the effectiveness of the restoration of GCase activity in macrophages from GBA-PD patients using pharmacological chaperone ambroxol. Background: Mutations…Blood–brain barrier breakdown in an adult mouse model of Parkinson’s disease
Objective: This study aims to evaluate the integrity of the blood-brain barrier (BBB) in parkinsonism. Background: Parkinson's disease (PD) is a neurodegenerative disorder which is…Prospective Characterization of Genetically Confirmed X-linked Dystonia Parkinsonism Patients and their Families: A 1 year longitudinal feasibility study
Objective: A one year feasibility study for a planned prospective longitudinal study of X-linked Dystonia-Parkinsonism patients and their families in rural Philippines. Background: X-linked dystonia…How Parkinson’s Disease Affects Value-Based Decisions
Objective: Parkinson’s Disease (PD) is a degenerative motor disease that causes subtle deficits in decision-making as a result of striatal dysfunction due to dopamine depletion.…Impulse Control Disorders in a Brazilian population with Parkinson´s disease -an observational study
Objective: To Analyse Impulse Control Disorders (ICDs) and Related Behaviors (RB) in 36 Brazilian patients with Parkinson´s disease (PD) and compare the cognition of the…Semantic Memory Assessment in Parkinson’s Disease
Objective: We assessed the performance of patients with a diagnosis of Parkinson’s disease (PD) in a series of semantic memory (SM) tasks including both living…Task difficulty and the three-stimulus oddball task in patients with PD
Objective: Examine the effect of task difficulty on event-related potentials (ERPs) in an oddball task in patients with PD. Background: In three-stimulus oddball tasks, some…
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