A phase IIa trial studying the safety and tolerability of IRL752 in patients with Parkinson’s disease dementia
Objective: The primary objective was to investigate the safety and tolerability of IRL752 in PD patients with dementia in a randomized controlled trial. Secondary outcome…The role of dysfunctional attentional processing in isolated minor hallucinations in Parkinson’s disease
Objective: To explore attentional processing deficits in Parkinson's disease (PD) with minor hallucinations using a selective visual attention task. Background: Recent literature points to a…Using whole genome sequencing and intronic sequence analysis to identify pathogenic variants in Parkin-related Parkinson’s Disease
Objective: To clarify the genetic cause of autosomal recessive early-onset Parkinson’s Disease (EOPD) for which only a single heterozygous coding mutation could be identified. Background:…Fragile X syndrome presenting with levodopa unresponsive parkinsonism
Objective: To describe a case of genetically confirmed Fragile X syndrome presenting with levodopa unresponsive Parkinsonism Background: Parkinsonism with or without ataxia is well recognised…A family of Phospholipase A2-associated neurodegeneration presented as complicated hereditary spastic paraplegia
Objective: To present reported two siblings of PLAN representing complicated HSP. Background: Neurodegeneration with brain iron accumulation (NBIA) is a group of diseases characterized by…Biomarkers of idiopathic REM sleep behavior disorder versus RBD within narcolepsy
Objective: We compared iRBD versus secondary RBD due to narcolepsy, searching for discriminating clinical, neurophysiological and pathological biomarkers. Background: Idiopathic REM sleep behavior disorder (iRBD)…“So much easier”; patient’s perceptions of Virtual Clinics for Parkinson’s Disease
Objective: Our virtual clinic for People with Parkinson’s disease (PwP) is a service innovation, providing a consultation with a Parkinson’s clinic doctor via telephone, with…Understanding the Needs and Concerns of Newly Diagnosed People with Parkinson’s Disease
Objective: To identify the concerns of those newly diagnosed with Parkinson’s (up to three years since diagnosis) through an online survey and utilize findings to inform…Relationship Between Handgrip and Functional Mobility in a Brazilian Parkinsonian Elderly Population
Objective: To evaluate and compare the grip strength and functional mobility of elderly people with different Hoehn and Yahr staging levels. Background: The proportion of elderly people…Prevalence of chronic kidney disease in patients with idiopathic Parkinson’s disease in a tertiary care hospital in Mexico City
Objective: To describe the prevalence of chronic kidney disease (CKD) in patients with idiopathic Parkinson's disease (PD) and to determine the association between renal function…
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