White Matter Hyperintensities and Mortality among Patients with Parkinsonism in Olmsted County, MN (1995-2010)
Objective: To examine white matter hyperintensity grade (WMHG) by parkinsonism type, and the association between WMHG and mortality among incident parkinsonism patients in a population-based…Neuroinflammation Predicts Dompaminergic Deficit in Early Parkinson Disease: DAT SPECT Imaging Study
Objective: We aimed to investigate whether striatal Dopamine transporter (DaT) uptake could be predicted by Neutrophil to lymphocyte ratio (NLR) or measures of disease severity…Effects of subthalamic nucleus deep brain stimulation in Parkinson’s disease are mediated by a prefronto-cerebellar-striatal loop
Objective: To determine DBS-related changes of a motor network using resting state fMRI in PD patients with chronic STN-DBS. Background: In Parkinson’s disease (PD), dopamine…Blink Recovery Pattern and Somatosensory Evoked Blink Reflex in patients with Parkinsonism syndromes
Objective: To assess somatosensory evoked blink reflex (SSEBR) and Blink Reflex recovery curve (BRrc) in patients with Parkinsonism Syndromes and compare it with normal control…Clinical features of Parkinson’s disease with and without rapid eye movement sleep behavior disorder
Objective: Study the relationship between RBD and other symptoms of PD. Background: Rapid eye movement sleep behavior disorder (RBD) and Parkinson’s disease (PD) are two…Non-motor outcomes of subthalamic DBS in PD depend on the location of volume of activated tissue
Objective: To investigate the impact of stimulation location on non-motor symptoms (NMS) in PD patients with DBS in the subthalamic nucleus (STN) via an analysis…Preliminary Study of Depression in Parkinson’s Disease with Diffusion Tensor Imaging
Objective: To explore the relationship between cognitive impairment in Parkinson’s Disease(PD) and the microstructure changes of brain region of interest(ROI) in diffusion tensor imaging(DTI). Background:…Visual hallucinations and autonomic burden are inversely associated with physical activity in PD
Objective: To determine the neuropsychiatric and non-motor correlates of reduced physical activity in PD. Background: The motor symptoms of PD interfere with patients’ ability to…The increased α-syn expression inhibits exosomal secretion
Objective: Exosomes, nano-sized extracellular vesicles, play an important role in many physiological processes in the central nervous system. Recently, we and others have demonstrated that…Unraveling gut microbiota in Parkinson’s disease and atypical parkinsonism
Objective: (1) To evaluate the differences in gut microbiota among Parkinson’s disease (PD), atypical parkinsonism (i.e. multiple system atrophy [MSA] and progressive supranuclear palsy [PSP])…
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