RBD predicts the cognitive impairment in Parkinson’s disease
Objective: To assess the relationship between the presence of Rapid eye movement sleep and behavior disorders RBD and the cognitive decline of non-demented patients with PD in…Validation of a performance-based assessment of functional ability related to cognition in Parkinson’s disease
Objective: Validate the University of California San Diego Performance-Based Skills Assessment (UPSA) in Parkinson's disease (PD) Background: Diagnostic criteria for PD dementia (PDD) require significant…Apolipoprotein E ε4 allele frequency in Korean Patients with Parkinson’s disease Dementia
Objective: The Apo E allele frequencies were evaluated in Korean patients with probable PDD diagnosed by the MDS task force criteria for the diagnosis of…A neuronal model of PARK20 (SYNJ1 mutation) using patient derived iPSCs
Objective: The SYNJ1 homozygous mutation (p.Arg258Gln) leads to juvenile Parkinsonism (PARK20). SYNJ1 plays an important role in synaptic vesicle cycling, and regulating autophagic flux. We…Genetic and pharmacological rescue of DJ-1 loss-of-function caused by a c.192G>C mutation in PARK7
Objective: In this study we investigate the cellular mechanism underlying the Parkinson’s disease (PD)-associated mutation c.192G>C in PARK7 and present a compound treatment that rescues…Absence of depression in de novo Parkinson’s disease: a benign motor phenotype?
Objective: This study aimed to assess the impact of early depression on motor deficits relative to the level of striatal dopaminergic depletion in patients with…Determinants of balance confidence and concern about falling in people with Parkinson’s disease
Objective: To identify factors that contribute to balance confidence and concern about falling in people with Parkinson’s disease (PD). Background: Reduced balance confidence and greater…Parkinsonics – A Prospective, Randomized, Blinded, Cross-Over Trial of Group Singing for Motor and Non-Motor Symptoms in Idiopathic Parkinson Disease (PD)
Objective: To assess the effects of weekly group singing on PD patients’ objective vocal and motoric function, cognition, mood, self-efficacy and quality of life. Background:…Evaluating the Experience of Diagnosis in Parkinson’s Disease
Objective: To evaluate a newly-designed diagnosis patient pathway for Parkinson’s disease, in terms of quality measures and patient satisfaction. Background: Receiving a diagnosis of Parkinson’s…Efficacy of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: results from the Phase 3 study dose-titration phase
Objective: To determine the dose of APL-130277 required by each patient with Parkinson’s Disease (PD) to turn from OFF to Full ON. This dose is…
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