Distinguishing Subclinical Postural Instability in Early-stage Parkinson disease and postural instability of normal elderly using Sensory Organization Test and Limit of Stability
Objective: To distinguish postural instability differences in Parkisnon disease patients and normal elderly patients with computerized dynamic posturography Background: Postural instability is a core symptom…Disease modeling for Perry syndrome using patient induced pluripotent stem cells
Objective: To develop a novel model of Perry syndrome using induced pluripotent stem cell (iPSC)-derived neurons. Background: Perry syndrome is a rare autosomal dominant disorder…Death in patients with Parkinson’s disease – an observational study
Objective: We aimed to analyse the major cause and contributory reasons for death in patients with Parkinson’s disease (PD) who were known to our PD…Disease severity is not predictive of the dose required for apomorphine sublingual film (APL-130277) to convert a patient with Parkinson’s disease(PD) from OFF to fully ON: Preliminary Results from a Phase III Study
Objective: To determine if baseline disease severity could be correlated to the effective dose of APL-130277 that was required to turn a patient with PD…Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
Objective: The purpose of this study was to identify potential plasma metabolic biomarkers for Parkinson’s disease (PD) Background: PD, characterized by a slowness of movement…Study Design for a Multi-Modal Approach to Understanding Parkinson’s Disease: The Personalized Parkinson Project
Objective: We aim to create a longitudinal dataset of clinical, molecular, imaging, and continuous wearable sensor-based data from a representative Parkinson’s disease (PD) cohort. Data…Quantitative demonstration of the efficacy of rotigotine transdermal patch in the treatment of nocturnal hypokinesia: A randomized, placebo-controlled trial using an axial inertial sensor
Objective: To evaluate the efficacy of rotigotine transdermal patch, using a wearable sensor, to treat PD patients with nocturnal immobility. Background: Nocturnal hypokinesia is a…Dopamine transporter imaging predicts motor response to dopaminergic therapy for patients with advanced Parkinson’s disease: Possible role in patient selection for subthalamic deep brain stimulation.
Objective: To investigate the possible role of dopamine transporter (DAT) imaging in patient selection for subthalamic deep brain stimulation (STN-DBS) surgery, we retrospectively investigated the…Clinical characteristics of scan without evidence of dopaminergic deficits (SWEDDs) in Japan.
Objective: To examine the clinical characteristics of SWEDDs and to compare to that of Parkinson’s disease (PD). Background: Patients with SWEDDs are defined as clinically…Impacts of White Matter Hyperintensities on Limit of Stability in Drug-naïve, de novo Patients with Idiopathic Parkinson’s Disease
Objective: The aims of this study were to investigate the effects of incidental white matter hyperintensities(WMH) on self-initiated postural control in drug-naïve, newly diagnosed Parkinson disease…
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