Probabilistic mapping of deep brain stimulation in Parkinson’s disease.
Objective: To find the neuroanatomical origins of deep brain stimulation (DBS) induced effects using probabilistic mapping. Background: While DBS of the subthalamic nucleus (STN) and…Pathological crying induced by deep brain stimulation of the subthalamic nucleus in Parkinsons’ disease
Objective: To report on a patient with Parkinsons’ disease (PD) who developed pathologic crying (PC) following chronic deep brain stimulation (DBS) of the subthalamic nucleus…Longitudinal study of freezing of gait in patients with Parkinson’s disease
Objective: We conducted a prospective hospital based cohort study to investigate the incidence of Freezing of gait (FOG) and variables associated with onset of FOG…The value of the Tau/α-synuclein ratio and TNF-α in cerebrospinal fluid, and of plasma IL-6, in the diagnosis and prognosis of Parkinson’s disease
Objective: To evaluate cerebrospinal fluid (CSF) levels of proteins associated with neuropathological inclusions and ratios among them and CSF and plasma levels of inflammation-related proteins…Insulin Resistance In Non-Diabetic People With Parkinson’s Disease
Objective: To study the incidence of insulin resistance (IR) in people with Parkinson's Disease (PD) and its relationship with motor and non-motor symptoms of the…PDSS: A Novel Mobile-based Parkinson Disease Severity Score
Objective: To propose a novel mobile-based Parkinson Disease Severity Score (PDSS) to provide high resolution and objective severity monitoring for patients in the home setting.…Neuroprotection and Alleviation of Parkinsonian Phenotypes by Ayurvedic Herbs
Objective: Our laboratory has focused on the herbal treatment of Parkinson’s disease especially by the above two common herbs Withania somnifera (Ws) and Mucuna pruriens…Effects of zonisamide, an anti-parkinsonian drug, on cognition and BPSD in DLB patients: A post-hoc analysis of DLB Ph2 study
Objective: Based on the results of a phase 2 study to evaluate the efficacy of zonisamide in improving parkinsonism accompanying dementia with Lewy Bodies (DLB),…Role of Apocyanin in modulating glial cell functions and associated inflammatory response in Lipopolysaccharide induced Parkinson’s disease model.
Objective: To explore the effect of apocyanin on glia mediated inflammatory response and α-synuclein aggregation in single intranigral LPS induced PD model Background: Converging lines…IGF-1 levels are associated with CSF pathology and executive dysfunction in de novo Parkinson’s disease patients
Objective: To investigate whether serum insulin-like growth factor-1 (IGF-1) is associated with clinical-neuropsychiatric, imaging and CSF markers of PD pathology in patients with early, drug-naïve…
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