- Effects of Arachidonyl-2′-chloroethylamide (ACEA), a selective CB1 receptor agonist, in MPTP mouse model of Parkinson’s diseaseObjective: Cannabinoids have been demonstrated to be effective in preclinical studies involving oxidative stress, neuroinflammation, and motor complications associated with Parkinson's disease (PD).The CB1 cannabinoid…
- Treatment of OFF episodes in Parkinson’s disease: An evaluation of physician practicesObjective: Determine physician practices into the treatment of OFF episodes in patients with Parkinson's disease PD. Background: OFF episodes are fairly common in patients with…
- Molecular landscape of Parkinson’s disease reveals a key role for lipids and lipoproteinsObjective: Integrate available genetic and expression data to generate a molecular landscape of Parkinson's disease (PD) in order to identify key disease mechanisms that may…
- Prevalence of restless legs syndrome in an atypical Parkinson’s disease populationObjective: The aim of this study was to determine the prevalence of Restless Legs Syndrome (RLS) in patients with Multiple Systems Atrophy (MSA), Corticobasilar Degeneration…
- Severe striatal and pallidal atrophy in early disease stages of X-linked dystonia-parkinsonismObjective: To investigate cortical and subcortical atrophy patterns in X-linked dystonia-parkinsonism (XDP). Background: XDP is a neurodegenerative disorder characterized by severe adult-onset dystonia followed by…
- Altered brain activation in complex walking conditions in patients with Parkinson’s diseaseObjective: To investigate (1) the differences in neural activation during complex walking that possesses different cognitive demands and (2) the influence of neurodegenerative disease as…
- Nigrostriatal degeneration and serum BDNF levels in patients with “de novo” untreated Parkinson’s diseaseObjective: To evaluate serum Brain-Derived NeurotrophicFactor(BDNF) levels in “de novo” untreated Parkinson's disease (PD) patients and their relationship to nigrostriatal degeneration measured with [123I]FP-CIT SPECT.…
- Functional deficits during response inhibition improve after dopaminergic medication for ParkinsonObjective: To study the neural correlates of impulse control in Parkinson's disease (PD) patients before and after the start of dopamine replacement therapy (follow up…
- Freezing of gait (FOG) in PD: Is electroencephalography (EEG) a gateway to elucidating the pathophysiology?Objective: To assess EEG changes in PD patients during episodes of FOG. Background: FOG is a paroxysmal phenomenon, a brief episodic marked reduction in forward…
- Improvement of saccade amplitude by the STN DBS and visual target eccentricityObjective: To investigate whether or not the improvement of saccade amplitude by the subthalamic nucleus (STN) deep brain stimulation (DBS) is the same for to…
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