Recognition of parkinsonism in African Americans in a community-based sample
Objective: To investigate recognition of parkinsonism in African Americans (AA) in a community-based sample in Chicago. Background: Prior studies suggest that the manifestation of parkinsonism…Quality of life of Parkinson’s disease patients in a tertiary hospital in Hong Kong
Objective: 1. To evaluate the quality of life (QoL) profile of Parkinson's disease (PD) patients in a multidisciplinary clinic in a tertiary hospital in Hong…My PD Journey: Experiences reported by people with Parkinson’s disease in several European countries – A quantitative and qualitative study
Objective: To document experience of service provision by people with Parkinson's disease (PD) care in Europe. Background: Developed by the EPDA, My PD Journey is…Survey of telemedicine use among MDS members
Objective: To evaluate telemedicine use amongst global members of the International Parkinson and Movement Disorders Society (MDS). Background: The current utilization of telemedicine by healthcare…A novel homozygous DJ1 mutation causes parkinsonism and ALS in a Turkish family
Objective: To present the clinical features and genetic findings of a Turkish family a new DJ1 mutation and presenting with early-onset levodopa responsive parkinsonism and…Gene network driven probable drug target identification: An in-silico study on Parkinson’s disease
Objective: Identification of probable drug targets. Background: Parkinson's disease, a motor system disorder, which manifests due to the loss of brain cells that produces dopamine.…Parkinson’s disease-associated Miro1 mutants cause mitochondrial dysfunction
Objective: In the present study we dissected the role of the first PD-associated mutations in RhoT1, the gene encoding for Miro1. Background: Commonly involved pathogenic…Speed and severity of toxicity induced by pre-formed α-synuclein fibrils in rat brain is enhanced by α-synuclein overexpression
Objective: To develop a physiologically relevant model of PD. Background: Intracerebral injection of pre-formed α-synuclein fibrils has emerged as an interesting tool to induce PD-like…Dysregulated macroautophagy and mitochondrial dynamics in PD with glucocerebrosidase mutations
Objective: To investigate markers of macroautophagy and mitochondrial dynamics in fibroblasts and postmortem brain of Parkinson's disease (PD) patients with glucoerebrosidase (GBA1) mutations and controls.…Diffusion tensor imaging (DTI) within the primate caudate nucleus marks dopaminergic (DA) and serotonergic (5-HT) lesions
Objective: To determine the best diffusion tensor imaging markers of dopaminergic and serotonergic lesions in the non-human primate. Background: DTI has received particular interest to…
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