Inflammatory profile discriminates clinical subtypes in LRRK2-associated PD
Objective: To evaluate whether inflammatory processes in PD patients with mutations in the LRRK2 gene (PD-LRRK2) are associated with modification of clinical features and disease…Do mutations in the TGM6 (SCA35) gene cause early-onset Parkinson’s disease?
Objective: To identify the genetic cause of early-onset Parkinson's disease (EOPD) in a Serbian family. Background: Hereditary EOPD is a genetically heterogeneous neurodegenerative disorder, characterized…Novel PLA2G6 c.1627C>T homozygous mutation and response to DBS-GPi
Objective: We present a novel homozygous PLA2G6 mutation and response to Deep Brain Stimulation (DBS). Background: Neurodegeneration with brain iron accumulation (NBIA) type 2/PLA2G6 is…Objective methods for quantifying the deep brain stimulation (DBS) efficacy in subthalamic-nuclei (STN) neurons with microelectrode recording (MER) technology
Objective: To design a computational modeling to develop a new diagnostic tool for effective neuro-medical-diagnostics for end users, to investigate and evaluate the potential benefits…Olfaction and gray matter volume in Parkinson’s disease. A voxel-based morphometry study
Objective: To evaluate the relation between olfactory functioning and gray matter (GM) volume in patients with Parkinson's disease (PD). Background: Olfactory impairment is one of…The impact of levodopa and apomorphine on beta- and gamma-oscillations in cortico-basal ganglia circuits in experimental parkinsonism
Objective: To clarify the role of pathologic oscillations in Parkinson's disease (PD) we recorded local field potentials (LFPs) in cortico-basal ganglia circuits of Parkinsonian and…Treatment of OFF episodes in Parkinson’s disease: An evaluation of patient and caregiver insights
Objective: Evaluate patient and caregiver opinions into the treatment of OFF episodes in patients with Parkinson's disease (PD). Background: OFF episodes are fairly common in…Colonic microbiome in Korean patients with Parkinson’s disease
Objective: In this study we investigated the relationship between colonic microbiome and clinical features of the patients with homogeneous ethnicity. Background: Colonic microbiome is an…Volumetry of the olfactory bulbs and tracts in the differential diagnosis of neurodegenerative parkinsonisms
Objective: The objective is to assess the use of the volumetry of OB & T as a parameter for distinguishing controls from patients with Parkinson's…Correlation analysis for postural instability and autonomic dysfunction in patients with Parkinson’s disease
Objective: To investigate correlation between postural instability and autonomic dysfunction in early stage Parkinson's disease patients. Background: Brainstem pathology may link postural instability (PI) and…
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