Presynaptic dopamine compartmentalization defects initiate auxilin-mediated parkinsonism
Objective: To evaluate the pathogenic mechanisms for auxilin-mediated Parkinson’s disease (PD). Background: Auxilin participates in uncoating of clathrin-coated vesicles (CCVs), thereby facilitating synaptic vesicle (SV)…Protective effects of Hibiscus sabdariffa extracts in 6-hydroxydopamine-lesioned parkinsonism.
Objective: The therapeutic effects of Hibiscus sabdariffa (HS) were investigated in parkinsonism rats induced by 6-hydroxydopamine (6-OHDA). Background: The oxidative stress is an important component…The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson’s Disease
Objective: To determine the feasibility and impact of remote cognitive remediation therapy (CRT) on cognitive function and quality of life (QOL) in patients with Parkinson’s…Diagnostic value of striatal [18F]-FP-DTBZ PET in Parkinson’s disease
Objective: To detect the difference of dopaminergic integrity between PDs and healthy controls (HC) using [18F]-FP-DTBZ PET in vivo and to obtain the diagnostic value…Amelioration of Levodopa-induced Dyskinesias using Genetic Silencing of Striatal CaV1.3 in Parkinsonian Rats: Impact of Sex and Advancing Age
Objective: To advance understanding of striatal CaV1.3 (cacna1d) channel silencing as a therapeutic approach to reduce levodopa-induced dyskinesias (LID), a side effect of long-term escalating…Activity and sleep associated with changes in glymphatic imaging-markers in Parkinson Disease patients enrolled in 3-month exercise program
Objective: To investigate whether intensity of activity and quality of sleep during a 3-month exercise program for patients with Parkinson Disease (PD) are associated with…The role of Parkinson Nurses for personalizing care in Parkinson’s Disease: a systematic review and meta-analysis
Objective: To identify the various roles and functions that Parkinson Nurses (PNs) may hold for personalized care of Patients with Parkinson’s (PwPs). Providing a systematic…Sleep Disorders in Normotensive Hydrocephalus
Objective: Objective of the work was to study the prevalence of sleep disorders, Rem Sleep Behaviour Disorder (RBD) and obstructive sleep apnea (OSA) in patients with NPH.…Whole-Exome Sequencing in a Movement Disorders Clinic
Objective: To evaluate the diagnostic utility of whole-exome sequencing (WES) in select patients with a movement disorder. Background: Many patients with suspected genetic movement disorders…The effect of Tuina in Traditional Chinese Medicine in treatment of Parkinson’s disease (Non-motor symptoms): a pilot clinical study
Objective: To evaluate the efficacy and safety of Tuina treatment in treating non-motor symptoms (NMS) of Parkinson’s disease (PD) and provide preliminary data for conducting…
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